Product Information
ISOTRETINOIN 20 MG CAPSULE is a generic product labeled by Mayne Pharma, priced at $1.8613 per EA under NDC 68308078230. Its NADAC has been published 129 times since Mar 6, 2024.
FDA first approved this application on Jan 19, 2012. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
20 mg/1
Manufacturer
Mayne PharmaNDC
68308078230
Classification
Generic
Dosage Form
CAPSULE, LIQUID FILLED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ISOTRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA076485FDA Approved
1/19/2012
TE Code
AB1
On Market Since
5/1/2012
Pharmacological Classes
Price Statistics
The NADAC for ISOTRETINOIN 20 MG CAPSULE has been published 129 times since Mar 6, 2024, and over the history we have for it it has declined 20.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.8613 per EA |
|---|---|
| All-time high | $2.7156 (Apr 10, 2024) |
| All-time low | $1.6918 (Jul 17, 2024) |
| 52-week high | $2.2069 |
| 52-week low | $1.7825 |
| Median price | $2.0564 |
| Average price | $2.0810 |
| Largest weekly change | +48.2% (Aug 21, 2024) |
| Weeks tracked | 129 |
| Tracking since | Mar 6, 2024 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ISOTRETINOIN 20 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for ISOTRETINOIN 20 MG CAPSULE, manufactured by Mayne Pharma, is $1.8613 per EA (NDC 68308078230), effective Aug 19, 2026.
How has the price of ISOTRETINOIN 20 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for ISOTRETINOIN 20 MG CAPSULE has declined 20.9%. It has been tracked across 129 weekly CMS publications since Mar 6, 2024.
What are the highest and lowest recorded NADAC prices for ISOTRETINOIN 20 MG CAPSULE?
Since Mar 6, 2024, the NADAC for ISOTRETINOIN 20 MG CAPSULE has ranged from a low of $1.6918 (Jul 17, 2024) to a high of $2.7156 (Apr 10, 2024), with a median of $2.0564 per EA.
Are there cheaper alternatives to ISOTRETINOIN 20 MG CAPSULE?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ISOTRETINOIN 20 MG CAPSULE in a comparable dosage form, but none are currently priced below it.
Who manufactures ISOTRETINOIN 20 MG CAPSULE?
ISOTRETINOIN 20 MG CAPSULE (NDC 68308078230) is labeled by Mayne Pharma, and CMS classifies it as a generic product.