Product Information
TRETINOIN 0.05% GEL is a generic product labeled by Oceanside Pharmaceuticals, priced at $4.1874 per GM under NDC 68682080045. Its NADAC has been published 513 times since Dec 9, 2015.
FDA first approved this application on Jul 26, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.05 g/100g
Manufacturer
Oceanside PharmaceuticalsNDC
68682080045
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
9/17/2025
Active Ingredients
TRETINOINApproval Type
Authorized Generic (NDA)
FDA Application
NDA022070FDA Approved
7/26/2007
TE Code
AB
On Market Since
7/26/2007
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.05% GEL has been published 513 times since Dec 9, 2015, and over the history we have for it it has declined 33.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $4.1874 per GM |
|---|---|
| All-time high | $6.5206 (Jan 13, 2016) |
| All-time low | $3.2879 (Nov 20, 2024) |
| 52-week high | $4.1874 |
| 52-week low | $4.0711 |
| Median price | $4.7931 |
| Average price | $4.7949 |
| Largest weekly change | +27.5% (Jun 19, 2024) |
| Weeks tracked | 513 |
| Tracking since | Dec 9, 2015 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
+2.9%
3Y
-0.1%
5Y
-24.9%
All
-33.2%
Last surveyed Oct 1, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TRETINOIN 0.05% GEL?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.05% GEL, manufactured by Oceanside Pharmaceuticals, is $4.1874 per GM (NDC 68682080045), effective Oct 1, 2025.
How has the price of TRETINOIN 0.05% GEL changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.05% GEL has declined 33.2%. It has been tracked across 513 weekly CMS publications since Dec 9, 2015.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.05% GEL?
Since Dec 9, 2015, the NADAC for TRETINOIN 0.05% GEL has ranged from a low of $3.2879 (Nov 20, 2024) to a high of $6.5206 (Jan 13, 2016), with a median of $4.7931 per GM.
Are there cheaper alternatives to TRETINOIN 0.05% GEL?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as TRETINOIN 0.05% GEL in a comparable dosage form, but none are currently priced below it.
Who manufactures TRETINOIN 0.05% GEL?
TRETINOIN 0.05% GEL (NDC 68682080045) is labeled by Oceanside Pharmaceuticals, and CMS classifies it as a generic product.