Back to Market Feed

Product Information

COMBIPATCH 0.05-0.25 MG PTCH is a brand product labeled by Noven Therapeutics, LLC, priced at $31.7925 per EA under NDC 68968052508. Its NADAC has been published 612 times since Dec 3, 2014.

FDA first approved this application on Aug 7, 1998.

COMBIPATCH 0.05-0.25 MG PTCH

estradiol/norethindrone acetate transdermal system
$31.7925per EA

Strength

.05; .25 mg/d; mg/d

NDC

68968052508

Classification

Brand

Dosage Form

PATCH, EXTENDED RELEASE

Route

TRANSDERMAL

Effective Date

8/19/2026

Approval Type

New Drug (NDA)

FDA Application

NDA020870

FDA Approved

8/7/1998

On Market Since

8/7/1998

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen
Progesterone Congeners
Progestin

Price Statistics

The NADAC for COMBIPATCH 0.05-0.25 MG PTCH has been published 612 times since Dec 3, 2014, and over the history we have for it it has risen 196.5%. The table below summarizes its recorded NADAC range and movement.

Current price$31.7925 per EA
All-time high$31.8397 (Jun 10, 2026)
All-time low$10.7217 (Dec 3, 2014)
52-week high$31.8397
52-week low$31.1527
Median price$24.8546
Average price$24.2824
Largest weekly change+24.9% (Jan 14, 2015)
Weeks tracked612
Tracking sinceDec 3, 2014

Price History

1W

-0.1%

1M

-0.1%

3M

-0.1%

6M

-0.1%

1Y

+2.0%

3Y

+11.6%

5Y

+20.3%

All

+196.5%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the estradiol/norethindrone acetate transdermal system market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Related Drugs

Same classification

ELESTRIN 0.06% GEL
Brand
00037480170•Viatris Specialty LLC
$3.6099
per GM
DIVIGEL 1.25 MG GEL PACKET
Brand
68025008630•Vertical Pharmaceuticals, LLC
$4.2906
per GM
DIVIGEL 1 MG GEL PACKET
Brand
68025006730•Vertical Pharmaceuticals, LLC
$5.3728
per GM
DIVIGEL 0.25 MG GEL PACKET
Brand
68025006530•Vertical Pharmaceuticals, LLC
$5.3877
per EA
DIVIGEL 0.75 MG GEL PACKET
Brand
68025008330•Vertical Pharmaceuticals, LLC
$5.3993
per EA
DIVIGEL 0.5 MG GEL PACKET
Brand
68025006630•Vertical Pharmaceuticals, LLC
$5.4149
per EA
ANGELIQ 0.5 MG-1 MG TABLET
Brand
50419048303•Bayer HealthCare Pharmaceuticals Inc.
$6.3701
per EA
ANGELIQ 0.25 MG-0.5 MG TABLET
Brand
50419048203•Bayer HealthCare Pharmaceuticals Inc.
$6.3713
per EA
DUAVEE 0.45-20 MG TABLET
Brand
00008112312•Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.
$6.4800
per EA
PREMARIN 0.9 MG TABLET
Brand
00046110381•Wyeth Pharmaceuticals LLC, a subsidiary of Pfizer Inc.
$6.9333
per EA

Frequently asked questions

What is the NADAC price of COMBIPATCH 0.05-0.25 MG PTCH?

The current National Average Drug Acquisition Cost (NADAC) for COMBIPATCH 0.05-0.25 MG PTCH, manufactured by Noven Therapeutics, LLC, is $31.7925 per EA (NDC 68968052508), effective Aug 19, 2026.

How has the price of COMBIPATCH 0.05-0.25 MG PTCH changed over time?

Over the history we have for it, the NADAC for COMBIPATCH 0.05-0.25 MG PTCH has risen 196.5%. It has been tracked across 612 weekly CMS publications since Dec 3, 2014.

What are the highest and lowest recorded NADAC prices for COMBIPATCH 0.05-0.25 MG PTCH?

Since Dec 3, 2014, the NADAC for COMBIPATCH 0.05-0.25 MG PTCH has ranged from a low of $10.7217 (Dec 3, 2014) to a high of $31.8397 (Jun 10, 2026), with a median of $24.8546 per EA.

Are there cheaper alternatives to COMBIPATCH 0.05-0.25 MG PTCH?

No other NADAC-published product currently shares the active ingredient and strength of COMBIPATCH 0.05-0.25 MG PTCH in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures COMBIPATCH 0.05-0.25 MG PTCH?

COMBIPATCH 0.05-0.25 MG PTCH (NDC 68968052508) is labeled by Noven Therapeutics, LLC, and CMS classifies it as a brand product.