Product Information
COMBIPATCH 0.05-0.25 MG PTCH is a brand product labeled by Noven Therapeutics, LLC, priced at $31.8190 per EA under NDC 68968052508. Its NADAC has been published 604 times since Dec 3, 2014.
Strength
.05; .25 mg/d; mg/d
Manufacturer
Noven Therapeutics, LLCNDC
68968052508
Classification
Brand
Dosage Form
PATCH, EXTENDED RELEASE
Route
TRANSDERMAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOL; NORETHINDRONE ACETATEApproval Type
New Drug (NDA)
FDA Application
NDA020870On Market Since
8/7/1998
Price Statistics
The NADAC for COMBIPATCH 0.05-0.25 MG PTCH has been published 604 times since Dec 3, 2014, and over the history we have for it it has risen 196.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $31.8190 per EA |
|---|---|
| All-time high | $31.8397 (Jun 10, 2026) |
| All-time low | $10.7217 (Dec 3, 2014) |
| 52-week high | $31.8397 |
| 52-week low | $31.1527 |
| Median price | $24.8546 |
| Average price | $24.1827 |
| Largest weekly change | +24.9% (Jan 14, 2015) |
| Weeks tracked | 604 |
| Tracking since | Dec 3, 2014 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the estradiol/norethindrone acetate transdermal system market page.
Lowest-Cost Alternatives
No alternatives available
Frequently asked questions
What is the NADAC price of COMBIPATCH 0.05-0.25 MG PTCH?
The current National Average Drug Acquisition Cost (NADAC) for COMBIPATCH 0.05-0.25 MG PTCH, manufactured by Noven Therapeutics, LLC, is $31.8190 per EA (NDC 68968052508), effective Jun 24, 2026.
How has the price of COMBIPATCH 0.05-0.25 MG PTCH changed over time?
Over the history we have for it, the NADAC for COMBIPATCH 0.05-0.25 MG PTCH has risen 196.8%. It has been tracked across 604 weekly CMS publications since Dec 3, 2014.
What are the highest and lowest recorded NADAC prices for COMBIPATCH 0.05-0.25 MG PTCH?
Since Dec 3, 2014, the NADAC for COMBIPATCH 0.05-0.25 MG PTCH has ranged from a low of $10.7217 (Dec 3, 2014) to a high of $31.8397 (Jun 10, 2026), with a median of $24.8546 per EA.
Are there cheaper alternatives to COMBIPATCH 0.05-0.25 MG PTCH?
No other NADAC-published product currently shares the active ingredient, strength, and dosage form of COMBIPATCH 0.05-0.25 MG PTCH, so no direct lower-cost alternative is listed.
Who manufactures COMBIPATCH 0.05-0.25 MG PTCH?
COMBIPATCH 0.05-0.25 MG PTCH (NDC 68968052508) is labeled by Noven Therapeutics, LLC, and CMS classifies it as a brand product.
Related Drugs
Same classification