Product Information
COMBIPATCH 0.05-0.25 MG PTCH is a brand product labeled by Noven Therapeutics, LLC, priced at $31.7862 per EA under NDC 68968052508. Its NADAC has been published 618 times since Dec 3, 2014.
FDA first approved this application on Aug 7, 1998.
Strength
.05; .25 mg/d; mg/d
Manufacturer
Noven Therapeutics, LLCNDC
68968052508
Classification
Brand
Dosage Form
PATCH, EXTENDED RELEASE
Route
TRANSDERMAL
Effective Date
9/23/2026
Active Ingredients
ESTRADIOL; NORETHINDRONE ACETATEApproval Type
New Drug (NDA)
FDA Application
NDA020870FDA Approved
8/7/1998
On Market Since
8/7/1998
Price Statistics
The NADAC for COMBIPATCH 0.05-0.25 MG PTCH has been published 618 times since Dec 3, 2014, and over the history we have for it it has risen 196.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $31.7862 per EA |
|---|---|
| All-time high | $31.8397 (Jun 10, 2026) |
| All-time low | $10.7217 (Dec 3, 2014) |
| 52-week high | $31.8397 |
| 52-week low | $31.1527 |
| Median price | $24.8588 |
| Average price | $24.3553 |
| Largest weekly change | +24.9% (Jan 14, 2015) |
| Weeks tracked | 618 |
| Tracking since | Dec 3, 2014 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the estradiol/norethindrone acetate transdermal system market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Noven Therapeutics, LLC manufacturer profile
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Drug market
estradiol/norethindrone acetate transdermal system market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Estrogen class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of COMBIPATCH 0.05-0.25 MG PTCH?
The current National Average Drug Acquisition Cost (NADAC) for COMBIPATCH 0.05-0.25 MG PTCH, manufactured by Noven Therapeutics, LLC, is $31.7862 per EA (NDC 68968052508), effective Sep 30, 2026.
How has the price of COMBIPATCH 0.05-0.25 MG PTCH changed over time?
Over the history we have for it, the NADAC for COMBIPATCH 0.05-0.25 MG PTCH has risen 196.5%. It has been tracked across 618 weekly CMS publications since Dec 3, 2014.
What are the highest and lowest recorded NADAC prices for COMBIPATCH 0.05-0.25 MG PTCH?
Since Dec 3, 2014, the NADAC for COMBIPATCH 0.05-0.25 MG PTCH has ranged from a low of $10.7217 (Dec 3, 2014) to a high of $31.8397 (Jun 10, 2026), with a median of $24.8588 per EA.
Are there cheaper alternatives to COMBIPATCH 0.05-0.25 MG PTCH?
No other NADAC-published product currently shares the active ingredient and strength of COMBIPATCH 0.05-0.25 MG PTCH in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures COMBIPATCH 0.05-0.25 MG PTCH?
COMBIPATCH 0.05-0.25 MG PTCH (NDC 68968052508) is labeled by Noven Therapeutics, LLC, and CMS classifies it as a brand product.