Product Information
THEOPHYLLINE ER 300 MG TABLET is a generic product labeled by Bionpharma Inc., priced at $0.3295 per EA under NDC 69452026720. Its NADAC has been published 134 times since Mar 13, 2024.
FDA first approved this application on Apr 26, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The Low Outlier badge above means this manufacturer's average price in the Theophylline market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
300 mg/1
Manufacturer
Bionpharma Inc.NDC
69452026720
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
THEOPHYLLINE ANHYDROUSApproval Type
Generic (ANDA)
FDA Application
ANDA216300FDA Approved
4/26/2023
TE Code
AB
On Market Since
10/12/2023
Pharmacological Classes
Price Statistics
The NADAC for THEOPHYLLINE ER 300 MG TABLET has been published 134 times since Mar 13, 2024, and over the history we have for it it has declined 79.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3295 per EA |
|---|---|
| All-time high | $1.5908 (Apr 10, 2024) |
| All-time low | $0.3196 (May 20, 2026) |
| 52-week high | $0.4924 |
| 52-week low | $0.3196 |
| Median price | $0.5660 |
| Average price | $0.6626 |
| Largest weekly change | +88.5% (Aug 21, 2024) |
| Weeks tracked | 134 |
| Tracking since | Mar 13, 2024 |
Generic Alternatives
The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Bionpharma Inc. manufacturer profile
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Drug market
Theophylline market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Methylxanthine class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of THEOPHYLLINE ER 300 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for THEOPHYLLINE ER 300 MG TABLET, manufactured by Bionpharma Inc., is $0.3295 per EA (NDC 69452026720), effective Sep 30, 2026.
How has the price of THEOPHYLLINE ER 300 MG TABLET changed over time?
Over the history we have for it, the NADAC for THEOPHYLLINE ER 300 MG TABLET has declined 79.1%. It has been tracked across 134 weekly CMS publications since Mar 13, 2024.
What are the highest and lowest recorded NADAC prices for THEOPHYLLINE ER 300 MG TABLET?
Since Mar 13, 2024, the NADAC for THEOPHYLLINE ER 300 MG TABLET has ranged from a low of $0.3196 (May 20, 2026) to a high of $1.5908 (Apr 10, 2024), with a median of $0.5660 per EA.
Are there cheaper alternatives to THEOPHYLLINE ER 300 MG TABLET?
9 manufacturers publish a NADAC-priced product with the same active ingredient and strength as THEOPHYLLINE ER 300 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures THEOPHYLLINE ER 300 MG TABLET?
THEOPHYLLINE ER 300 MG TABLET (NDC 69452026720) is labeled by Bionpharma Inc., and CMS classifies it as a generic product.