Product Information

THEOPHYLLINE ER 300 MG TABLET is a generic product labeled by Teva Pharmaceuticals USA Inc., priced at $0.3422 per EA under NDC 00480331001. Its NADAC has been published 180 times since Mar 15, 2023.

FDA first approved this application on Oct 12, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

THEOPHYLLINE ER 300 MG TABLET

Theophylline
$0.3422per EA

Strength

300 mg/1

NDC

00480331001

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

THEOPHYLLINE

Approval Type

Generic (ANDA)

FDA Application

ANDA216961

FDA Approved

10/12/2022

TE Code

AB

On Market Since

1/27/2023

Pharmacological Classes

Price Statistics

The NADAC for THEOPHYLLINE ER 300 MG TABLET has been published 180 times since Mar 15, 2023, and over the history we have for it it has declined 86.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3422 per EA
All-time high$2.6814 (Jun 14, 2023)
All-time low$0.3196 (May 20, 2026)
52-week high$0.5576
52-week low$0.3196
Median price$0.6295
Average price$1.0632
Largest weekly change+88.5% (Aug 21, 2024)
Weeks tracked180
Tracking sinceMar 15, 2023

Price History

1W

+5.5%

1M

+5.5%

3M

+7.0%

6M

-15.4%

1Y

-38.6%

3Y

-84.2%

5Y

N/A

All

-86.5%

Generic Alternatives

The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of THEOPHYLLINE ER 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for THEOPHYLLINE ER 300 MG TABLET, manufactured by Teva Pharmaceuticals USA Inc., is $0.3422 per EA (NDC 00480331001), effective Aug 19, 2026.

How has the price of THEOPHYLLINE ER 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for THEOPHYLLINE ER 300 MG TABLET has declined 86.5%. It has been tracked across 180 weekly CMS publications since Mar 15, 2023.

What are the highest and lowest recorded NADAC prices for THEOPHYLLINE ER 300 MG TABLET?

Since Mar 15, 2023, the NADAC for THEOPHYLLINE ER 300 MG TABLET has ranged from a low of $0.3196 (May 20, 2026) to a high of $2.6814 (Jun 14, 2023), with a median of $0.6295 per EA.

Are there cheaper alternatives to THEOPHYLLINE ER 300 MG TABLET?

9 manufacturers publish a NADAC-priced product with the same active ingredient and strength as THEOPHYLLINE ER 300 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures THEOPHYLLINE ER 300 MG TABLET?

THEOPHYLLINE ER 300 MG TABLET (NDC 00480331001) is labeled by Teva Pharmaceuticals USA Inc., and CMS classifies it as a generic product.