Product Information

THEOPHYLLINE ER 300 MG TABLET is a generic product labeled by Heritage Pharmaceuticals Inc., priced at $0.3422 per EA under NDC 23155074101. Its NADAC has been published 202 times since Oct 12, 2022.

FDA first approved this application on Apr 30, 1990. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

THEOPHYLLINE ER 300 MG TABLET

Theophylline
$0.3422per EA

Strength

300 mg/1

NDC

23155074101

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

THEOPHYLLINE ANHYDROUS

Approval Type

Generic (ANDA)

FDA Application

ANDA089763

FDA Approved

4/30/1990

TE Code

AB

On Market Since

6/27/2022

Pharmacological Classes

Price Statistics

The NADAC for THEOPHYLLINE ER 300 MG TABLET has been published 202 times since Oct 12, 2022, and over the history we have for it it has declined 88.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3422 per EA
All-time high$2.9916 (Oct 12, 2022)
All-time low$0.3196 (May 20, 2026)
52-week high$0.5576
52-week low$0.3196
Median price$0.9944
Average price$1.2344
Largest weekly change+88.5% (Aug 21, 2024)
Weeks tracked202
Tracking sinceOct 12, 2022

Price History

1W

+5.5%

1M

+5.5%

3M

+7.0%

6M

-15.4%

1Y

-38.6%

3Y

-84.2%

5Y

N/A

All

-88.6%

Generic Alternatives

The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of THEOPHYLLINE ER 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for THEOPHYLLINE ER 300 MG TABLET, manufactured by Heritage Pharmaceuticals Inc., is $0.3422 per EA (NDC 23155074101), effective Aug 19, 2026.

How has the price of THEOPHYLLINE ER 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for THEOPHYLLINE ER 300 MG TABLET has declined 88.6%. It has been tracked across 202 weekly CMS publications since Oct 12, 2022.

What are the highest and lowest recorded NADAC prices for THEOPHYLLINE ER 300 MG TABLET?

Since Oct 12, 2022, the NADAC for THEOPHYLLINE ER 300 MG TABLET has ranged from a low of $0.3196 (May 20, 2026) to a high of $2.9916 (Oct 12, 2022), with a median of $0.9944 per EA.

Are there cheaper alternatives to THEOPHYLLINE ER 300 MG TABLET?

9 manufacturers publish a NADAC-priced product with the same active ingredient and strength as THEOPHYLLINE ER 300 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures THEOPHYLLINE ER 300 MG TABLET?

THEOPHYLLINE ER 300 MG TABLET (NDC 23155074101) is labeled by Heritage Pharmaceuticals Inc., and CMS classifies it as a generic product.