Product Information

BUPROPION HCL XL 300 MG TABLET is a generic product labeled by Granules Pharmaceuticals Inc., priced at $0.1115 per EA under NDC 70010078505. Its NADAC has been published 103 times since Jul 10, 2024.

BUPROPION HCL XL 300 MG TABLET

Bupropion hydrochloride
$0.1115per EA

Strength

300 mg/1

NDC

70010078505

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA215568

On Market Since

12/15/2022

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 103 times since Jul 10, 2024, and over the history we have for it it has declined 33.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1115 per EA
All-time high$0.1676 (Jul 10, 2024)
All-time low$0.1033 (Feb 18, 2026)
52-week high$0.1504
52-week low$0.1033
Median price$0.1443
Average price$0.1369
Largest weekly change-23.7% (Nov 20, 2024)
Weeks tracked103
Tracking sinceJul 10, 2024

Price History

1W

0.0%

1M

-3.4%

3M

+3.9%

6M

-11.5%

1Y

-25.9%

3Y

N/A

5Y

N/A

All

-33.5%

Generic Alternatives

The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 7% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by Granules Pharmaceuticals Inc., is $0.1115 per EA (NDC 70010078505), effective Jun 24, 2026.

How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 33.5%. It has been tracked across 103 weekly CMS publications since Jul 10, 2024.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?

Since Jul 10, 2024, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1033 (Feb 18, 2026) to a high of $0.1676 (Jul 10, 2024), with a median of $0.1443 per EA.

Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?

Yes. 6 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, BUPROPION HCL XL 300 MG TABLET, is $0.1033 per EA — about 7% below BUPROPION HCL XL 300 MG TABLET.

Who manufactures BUPROPION HCL XL 300 MG TABLET?

BUPROPION HCL XL 300 MG TABLET (NDC 70010078505) is labeled by Granules Pharmaceuticals Inc., and CMS classifies it as a generic product.