Fluconazole
63 NDCs across 14 manufacturers|63 Generic,0 Brand
Fluconazole is used to treat aids-related opportunistic infections, blastomycosis, chronic mucocutaneous candidiasis, oral candidiasis, vulvovaginal candidiasis and coccidioidomycosis, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on Jan 29, 1990, and the first generic was approved Jul 29, 2004. FDA's Orange Book lists 41 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $38 million on Fluconazole across 3.8 million claims for 2.2 million beneficiaries.
Fluconazole is available as 63 NDCs from 14 manufacturers (63 generic, 0 brand), with NADAC prices from $0.21 to $1.95 per EA — the most expensive product costs about 9.4× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
63
63G / 0B
Manufacturers
14
competing in market
Price Spread
$0.21 – $1.95
per EA, 54 of 63 NDCs
7d Activity
avg +0.9% WoW · of 63 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
NorthStar Rx LLC manufacturer profile
Open the supplier page for the manufacturer with the strongest footprint in this market.
Lead class
Azole Antifungal class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
14 manufacturers producing FLUCONAZOLE(2 pricing outliers)
Frequently Asked Questions
What is Fluconazole used to treat?
Fluconazole is used to treat aids-related opportunistic infections, blastomycosis, chronic mucocutaneous candidiasis, oral candidiasis, vulvovaginal candidiasis and coccidioidomycosis, per the National Library of Medicine's MED-RT classification.
When did Fluconazole become available as a generic?
FDA approved the first generic Fluconazole (ANDA) on Jul 29, 2004. The Orange Book currently lists 41 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Fluconazole?
In 2024, Medicare Part D spent $38 million on Fluconazole across 3.8 million claims for 2.2 million beneficiaries.
How many Fluconazole products are on the market?
The Fluconazole drug market contains 63 NDCs from 14 manufacturers — 63 generic and 0 brand products.
What is the price range for Fluconazole?
NADAC reference prices for Fluconazole range from $0.2076 to $1.9486 per EA — the most expensive product costs about 9.4× the cheapest. 9 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.
Which manufacturers make Fluconazole?
14 manufacturers list Fluconazole in NADAC. Ranked by number of NDCs, the largest are NorthStar Rx LLC (8), Rising Pharma Holdings Inc. (7), Dr. Reddy's Laboratories Inc. (7), Zydus Pharmaceuticals (USA) Inc. (7), Aurobindo Pharma Limited (6).
How has the price of Fluconazole changed recently?
Over the past 7 days, 23 Fluconazole NDCs rose and 34 fell, with a market-wide average change of +0.9%.