Nystatin

60 NDCs across 21 manufacturers|60 Generic,0 Brand

Nystatin is used to treat chronic mucocutaneous candidiasis, cutaneous candidiasis, oral candidiasis and vulvovaginal candidiasis, per the National Library of Medicine's MED-RT classification.

▸ More about this market

The brand product was first FDA-approved before 1982, and the first generic was approved Jan 1, 1982. In 2024, Medicare Part D spent $77 million on Nystatin across 3.9 million claims for 2.1 million beneficiaries.

Nystatin is available as 60 NDCs from 21 manufacturers (60 generic, 0 brand), with NADAC prices from $0.16 to $0.45 per GM — the most expensive product costs about 2.9× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.

Total NDCs

60G / 0B

Manufacturers

competing in market

Price Spread

$0.16 – $0.45

per GM, 41 of 60 NDCs

7d Activity

24↑22↓14 flat

avg +0.2% WoW · of 60 NDCs

Market Price Trend

Monthly average NADAC per unit, split by generic and brand.

Manufacturer Breakdown

21 manufacturers producing NYSTATIN

Macleods Pharmaceuticals Limited

4 NDCs

$0.2071

avg/unit

Torrent Pharmaceuticals Limited

4 NDCs

$0.2071

avg/unit

Padagis Israel Pharmaceuticals Ltd

Upsher-Smith Laboratories LLC

Zydus Pharmaceuticals (USA) Inc.

Dr. Reddy's Laboratories Inc.

Viona Pharmaceuticals Inc.

Major Pharmaceuticals

2 NDCs

$0.2012

avg/unit

Sun Pharmaceutical Industries Inc.

2 NDCs

$0.1782

avg/unit

Taro Pharmaceuticals U.S.A. Inc.

2 NDCs

$0.1093

avg/unit

Pharmaceutical Associates, Inc.

2 NDCs

$0.0913

avg/unit

Teva Pharmaceuticals USA Inc.

1 NDC

$0.3925

avg/unit

Heritage Pharmaceuticals Inc.

1 NDC

$0.3925

avg/unit

American Health Packaging

1 NDC

$0.1755

avg/unit

Drug Portfolio

60 NDCs total, 60 shown

Drug ↕	NDC	Manufacturer ↕	Price	Market Outlier	Class	7d Change ↕	Therapeutic Class
NYSTATIN 100,000 UNIT/GM POWD	68308015215	Mayne Pharma	$0.4455 per GM	—	Generic	—	Polyene Antifungal
NYAMYC 100,000 UNIT/GM POWDER	00832046515	Upsher-Smith Laboratories LLC	$0.4365 per GM	—	Generic	+0.86%	Polyene Antifungal
NYSTOP 100,000 UNIT/GM POWDER	00574200815	Padagis US LLC	$0.4365 per GM	—	Generic	+0.86%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	68382037001	Zydus Pharmaceuticals (USA) Inc.	$0.4365 per GM	—	Generic	+0.86%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	69315030615	Leading Pharma, LLC	$0.4365 per GM	—	Generic	+0.86%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	72603049101	NorthStar Rx LLC	$0.4365 per GM	—	Generic	+0.86%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	75907006044	Dr. Reddy's Laboratories Inc.	$0.4365 per GM	—	Generic	+0.86%	Polyene Antifungal
NYSTATIN 500,000 UNIT ORAL TAB	62135074190	Chartwell RX LLC	$0.3925 per EA	—	Generic	+3.36%	Polyene Antifungal
NYSTATIN 500,000 UNIT ORAL TAB	00093098301	Teva Pharmaceuticals USA Inc.	$0.3925 per EA	—	Generic	+3.36%	Polyene Antifungal
NYSTATIN 500,000 UNIT ORAL TAB	23155005101	Heritage Pharmaceuticals Inc.	$0.3925 per EA	—	Generic	+3.36%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM OINT	69315030715	Leading Pharma, LLC	$0.3345 per GM	—	Generic	—	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	68308015230	Mayne Pharma	$0.3241 per GM	—	Generic	—	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	69315030630	Leading Pharma, LLC	$0.3119 per GM	—	Generic	+1.81%	Polyene Antifungal
NYAMYC 100,000 UNIT/GM POWDER	00832046530	Upsher-Smith Laboratories LLC	$0.3119 per GM	—	Generic	+1.81%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	68382037002	Zydus Pharmaceuticals (USA) Inc.	$0.3119 per GM	—	Generic	+1.81%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	75907006030	Dr. Reddy's Laboratories Inc.	$0.3119 per GM	—	Generic	+1.81%	Polyene Antifungal
NYSTOP 100,000 UNIT/GM POWDER	00574200830	Padagis US LLC	$0.3119 per GM	—	Generic	+1.81%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	72603049102	NorthStar Rx LLC	$0.3119 per GM	—	Generic	+1.81%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM OINT	69315030730	Leading Pharma, LLC	$0.2776 per GM	—	Generic	—	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	68308015260	Mayne Pharma	$0.2755 per GM	—	Generic	—	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	69315030660	Leading Pharma, LLC	$0.2587 per GM	—	Generic	-1.18%	Polyene Antifungal
NYSTOP 100,000 UNIT/GM POWDER	00574200802	Padagis US LLC	$0.2587 per GM	—	Generic	-1.18%	Polyene Antifungal
NYAMYC 100,000 UNIT/GM POWDER	00832046560	Upsher-Smith Laboratories LLC	$0.2587 per GM	—	Generic	-1.18%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	75907006060	Dr. Reddy's Laboratories Inc.	$0.2587 per GM	—	Generic	-1.18%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	72603049103	NorthStar Rx LLC	$0.2587 per GM	—	Generic	-1.18%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM POWD	68382037003	Zydus Pharmaceuticals (USA) Inc.	$0.2587 per GM	—	Generic	-1.18%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM OINT	33342048130	Macleods Pharmaceuticals Limited	$0.2431 per GM	—	Generic	+0.46%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM OINT	72578008904	Viona Pharmaceuticals Inc.	$0.2431 per GM	—	Generic	+0.46%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM OINT	00472016630	Actavis Pharma, Inc.	$0.2431 per GM	—	Generic	+0.46%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM OINT	13668053402	Torrent Pharmaceuticals Limited	$0.2431 per GM	—	Generic	+0.46%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM OINT	45802004811	Padagis Israel Pharmaceuticals Ltd	$0.2431 per GM	—	Generic	+0.46%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM OINT	00472016615	Actavis Pharma, Inc.	$0.2291 per GM	—	Generic	-2.72%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM OINT	33342048115	Macleods Pharmaceuticals Limited	$0.2291 per GM	—	Generic	-2.72%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM OINT	13668053401	Torrent Pharmaceuticals Limited	$0.2291 per GM	—	Generic	-2.72%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM OINT	72578008901	Viona Pharmaceuticals Inc.	$0.2291 per GM	—	Generic	-2.72%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM OINT	45802004835	Padagis Israel Pharmaceuticals Ltd	$0.2291 per GM	—	Generic	-2.72%	Polyene Antifungal
NYSTATIN 500,000 UNIT/5 ML CUP	00121086850	PAI Holdings LLC	$0.2269 per ML	—	Generic	—	Polyene Antifungal
NYSTATIN 500,000 UNIT/5 ML CUP	00904727692	Major Pharmaceuticals	$0.2269 per ML	—	Generic	—	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM CREAM	51672128901	Sun Pharmaceutical Industries Inc.	$0.2004 per GM	—	Generic	+2.66%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM CREAM	45802005935	Padagis Israel Pharmaceuticals Ltd	$0.2004 per GM	—	Generic	+2.66%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM CREAM	33342046915	Macleods Pharmaceuticals Limited	$0.2004 per GM	—	Generic	+2.66%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM CREAM	13668059501	Torrent Pharmaceuticals Limited	$0.2004 per GM	—	Generic	+2.66%	Polyene Antifungal
NYSTATIN 500,000 UNIT/5 ML CUP	00904727670	Major Pharmaceuticals	$0.1755 per ML	—	Generic	—	Polyene Antifungal
NYSTATIN 500,000 UNIT/5 ML CUP	00121086800	PAI Holdings LLC	$0.1755 per ML	—	Generic	—	Polyene Antifungal
NYSTATIN 500,000 UNIT/5 ML CUP	60687080017	American Health Packaging	$0.1755 per ML	—	Generic	—	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM CREAM	33342046930	Macleods Pharmaceuticals Limited	$0.1559 per GM	—	Generic	-1.00%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM CREAM	45802005911	Padagis Israel Pharmaceuticals Ltd	$0.1559 per GM	—	Generic	-1.00%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM CREAM	13668059502	Torrent Pharmaceuticals Limited	$0.1559 per GM	—	Generic	-1.00%	Polyene Antifungal
NYSTATIN 100,000 UNIT/GM CREAM	51672128902	Sun Pharmaceutical Industries Inc.	$0.1559 per GM	—	Generic	-1.00%	Polyene Antifungal
NYSTATIN 100,000 UNIT/ML SUSP	51672411704	Taro Pharmaceuticals U.S.A. Inc.	$0.1426 per ML	—	Generic	—	Polyene Antifungal
NYSTATIN 100,000 UNIT/ML SUSP	69315050460	Leading Pharma, LLC	$0.1401 per ML	—	Generic	-1.55%	Polyene Antifungal
NYSTATIN 100,000 UNIT/ML SUSP	62135081346	Chartwell RX LLC	$0.1401 per ML	—	Generic	-1.55%	Polyene Antifungal
NYSTATIN 100,000 UNIT/ML SUSP	00121086802	PAI Holdings LLC	$0.1401 per ML	—	Generic	-1.55%	Polyene Antifungal
NYSTATIN 100,000 UNIT/ML SUSP	00121081002	Pharmaceutical Associates, Inc.	$0.1264 per ML	—	Generic	—	Polyene Antifungal
NYSTATIN 100,000 UNIT/ML SUSP	51672411709	Taro Pharmaceuticals U.S.A. Inc.	$0.0761 per ML	—	Generic	—	Polyene Antifungal
NYSTATIN 100,000 UNIT/ML SUSP	00121104516	PAI Holdings LLC	$0.0584 per ML	—	Generic	-0.20%	Polyene Antifungal
NYSTATIN 100,000 UNIT/ML SUSP	62135081347	Chartwell RX LLC	$0.0584 per ML	—	Generic	-0.20%	Polyene Antifungal
NYSTATIN 100,000 UNIT/ML SUSP	69315050447	Leading Pharma, LLC	$0.0584 per ML	—	Generic	-0.20%	Polyene Antifungal
NYSTATIN 100,000 UNIT/ML SUSP	00121086816	PAI Holdings LLC	$0.0584 per ML	—	Generic	-0.20%	Polyene Antifungal
NYSTATIN 100,000 UNIT/ML SUSP	00121081016	Pharmaceutical Associates, Inc.	$0.0561 per ML	—	Generic	—	Polyene Antifungal

Frequently Asked Questions

What is Nystatin used to treat?

Nystatin is used to treat chronic mucocutaneous candidiasis, cutaneous candidiasis, oral candidiasis and vulvovaginal candidiasis, per the National Library of Medicine's MED-RT classification.

When did Nystatin become available as a generic?

FDA approved the first generic Nystatin (ANDA) on Jan 1, 1982.

How much does Medicare spend on Nystatin?

In 2024, Medicare Part D spent $77 million on Nystatin across 3.9 million claims for 2.1 million beneficiaries.

How many Nystatin products are on the market?

The Nystatin drug market contains 60 NDCs from 21 manufacturers — 60 generic and 0 brand products.

What is the price range for Nystatin?

NADAC reference prices for Nystatin range from $0.1559 to $0.4455 per GM — the most expensive product costs about 2.9× the cheapest. 19 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.

Which manufacturers make Nystatin?

21 manufacturers list Nystatin in NADAC. Ranked by number of NDCs, the largest are Leading Pharma, LLC (7), PAI Holdings LLC (5), Macleods Pharmaceuticals Limited (4), Torrent Pharmaceuticals Limited (4), Padagis Israel Pharmaceuticals Ltd (4).

How has the price of Nystatin changed recently?

Over the past 7 days, 24 Nystatin NDCs rose and 22 fell, with a market-wide average change of +0.2%.