Product Information
METHOTREXATE 50 MG/2 ML VIAL is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $1.2431 per ML under NDC 00143951910. Its NADAC has been published 212 times since Apr 11, 2018.
Strength
25 mg/mL
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00143951910
Classification
Generic
Dosage Form
SOLUTION
Route
INTRA-ARTERIAL; INTRAMUSCULAR; INTRATHECAL; INTRAVENOUS
Last Updated
6/17/2026
Active Ingredients
METHOTREXATEApproval Type
Generic (ANDA)
FDA Application
ANDA089340On Market Since
10/10/2017
Pharmacological Classes
Price Statistics
The NADAC for METHOTREXATE 50 MG/2 ML VIAL has been published 212 times since Apr 11, 2018, and over the history we have for it it has declined 27.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.2431 per ML |
|---|---|
| All-time high | $1.7314 (Jul 11, 2018) |
| All-time low | $1.1511 (Jan 17, 2024) |
| 52-week high | $1.3862 |
| 52-week low | $1.2060 |
| Median price | $1.3518 |
| Average price | $1.3717 |
| Largest weekly change | +14.9% (Feb 21, 2024) |
| Weeks tracked | 212 |
| Tracking since | Apr 11, 2018 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 48% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of METHOTREXATE 50 MG/2 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 50 MG/2 ML VIAL, manufactured by Hikma Pharmaceuticals USA Inc., is $1.2431 per ML (NDC 00143951910), effective Jun 24, 2026.
How has the price of METHOTREXATE 50 MG/2 ML VIAL changed over time?
Over the history we have for it, the NADAC for METHOTREXATE 50 MG/2 ML VIAL has declined 27.6%. It has been tracked across 212 weekly CMS publications since Apr 11, 2018.
What are the highest and lowest recorded NADAC prices for METHOTREXATE 50 MG/2 ML VIAL?
Since Apr 11, 2018, the NADAC for METHOTREXATE 50 MG/2 ML VIAL has ranged from a low of $1.1511 (Jan 17, 2024) to a high of $1.7314 (Jul 11, 2018), with a median of $1.3518 per ML.
Are there cheaper alternatives to METHOTREXATE 50 MG/2 ML VIAL?
Yes. 3 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, METHOTREXATE 1 GRAM/40 ML VIAL, is $0.6450 per ML — about 48% below METHOTREXATE 50 MG/2 ML VIAL.
Who manufactures METHOTREXATE 50 MG/2 ML VIAL?
METHOTREXATE 50 MG/2 ML VIAL (NDC 00143951910) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.
Related Drugs
Same classification