Historical record - last NADAC effective date: 11/19/2014

This NDC is on FDA's drug shortage list (posted Mar 13, 2023)

Product Information

METHOTREXATE 1 GRAM/40 ML VIAL is a generic product labeled by Hospira Inc., priced at $0.6450 per ML under NDC 61703040825. Its NADAC has been published 77 times since Jul 2, 2014.

FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AP.

METHOTREXATE 1 GRAM/40 ML VIAL

Methotrexate
$0.6450per ML

Strength

25 mg/mL

Manufacturer

Hospira Inc.

NDC

61703040825

Classification

Generic

Dosage Form

INJECTION, SOLUTION

Route

INTRAMUSCULAR; INTRATHECAL; INTRAVENOUS; SUBCUTANEOUS

Effective Date

11/19/2014

Active Ingredients

METHOTREXATE SODIUM

Approval Type

New Drug (NDA)

FDA Application

NDA011719

FDA Approved

Before 1982

TE Code

AP

On Market Since

11/11/2013

Pharmacological Classes

Folate Analog Metabolic Inhibitor
Folic Acid Metabolism Inhibitors

Price Statistics

The NADAC for METHOTREXATE 1 GRAM/40 ML VIAL has been published 77 times since Jul 2, 2014, and over the history we have for it it has declined 29.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.6450 per ML
All-time high$0.9146 (Nov 12, 2014)
All-time low$0.6450 (Nov 19, 2014)
Median price$0.6450
Average price$0.7150
Largest weekly change-29.5% (Nov 19, 2014)
Weeks tracked77
Tracking sinceJul 2, 2014

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

N/A

3Y

N/A

5Y

N/A

All

-29.5%

Last surveyed Dec 16, 2015 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METHOTREXATE 1 GRAM/40 ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 1 GRAM/40 ML VIAL, manufactured by Hospira Inc., is $0.6450 per ML (NDC 61703040825), effective Dec 16, 2015.

How has the price of METHOTREXATE 1 GRAM/40 ML VIAL changed over time?

Over the history we have for it, the NADAC for METHOTREXATE 1 GRAM/40 ML VIAL has declined 29.5%. It has been tracked across 77 weekly CMS publications since Jul 2, 2014.

What are the highest and lowest recorded NADAC prices for METHOTREXATE 1 GRAM/40 ML VIAL?

Since Jul 2, 2014, the NADAC for METHOTREXATE 1 GRAM/40 ML VIAL has ranged from a low of $0.6450 (Nov 19, 2014) to a high of $0.9146 (Nov 12, 2014), with a median of $0.6450 per ML.

Are there cheaper alternatives to METHOTREXATE 1 GRAM/40 ML VIAL?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METHOTREXATE 1 GRAM/40 ML VIAL in a comparable dosage form, but none are currently priced below it.

Who manufactures METHOTREXATE 1 GRAM/40 ML VIAL?

METHOTREXATE 1 GRAM/40 ML VIAL (NDC 61703040825) is labeled by Hospira Inc., and CMS classifies it as a generic product.

Is METHOTREXATE 1 GRAM/40 ML VIAL in shortage?

Yes — NDC 61703040825 is currently listed in FDA's drug shortage database (posted Mar 13, 2023).