Product Information

METHOTREXATE 2.5 MG TABLET is a generic product labeled by Alembic Pharmaceuticals Inc., priced at $0.1566 per EA under NDC 62332073036. Its NADAC has been published 101 times since Sep 18, 2024.

FDA first approved this application on Jun 3, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METHOTREXATE 2.5 MG TABLET

METHOTREXATE
$0.1566per EA

Strength

2.5 mg/1

NDC

62332073036

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

METHOTREXATE SODIUM

Approval Type

Generic (ANDA)

FDA Application

ANDA217552

FDA Approved

6/3/2024

TE Code

AB

On Market Since

6/4/2024

Pharmacological Classes

Folate Analog Metabolic Inhibitor
Folic Acid Metabolism Inhibitors

Price Statistics

The NADAC for METHOTREXATE 2.5 MG TABLET has been published 101 times since Sep 18, 2024, and over the history we have for it it has declined 10.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1566 per EA
All-time high$0.1754 (Oct 16, 2024)
All-time low$0.1530 (Nov 19, 2025)
52-week high$0.1694
52-week low$0.1530
Median price$0.1611
Average price$0.1619
Largest weekly change-7.0% (Nov 20, 2024)
Weeks tracked101
Tracking sinceSep 18, 2024

Price History

1W

-1.1%

1M

-1.1%

3M

-4.6%

6M

-2.3%

1Y

-7.6%

3Y

N/A

5Y

N/A

All

-10.7%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METHOTREXATE 2.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 2.5 MG TABLET, manufactured by Alembic Pharmaceuticals Inc., is $0.1566 per EA (NDC 62332073036), effective Aug 19, 2026.

How has the price of METHOTREXATE 2.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for METHOTREXATE 2.5 MG TABLET has declined 10.7%. It has been tracked across 101 weekly CMS publications since Sep 18, 2024.

What are the highest and lowest recorded NADAC prices for METHOTREXATE 2.5 MG TABLET?

Since Sep 18, 2024, the NADAC for METHOTREXATE 2.5 MG TABLET has ranged from a low of $0.1530 (Nov 19, 2025) to a high of $0.1754 (Oct 16, 2024), with a median of $0.1611 per EA.

Are there cheaper alternatives to METHOTREXATE 2.5 MG TABLET?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as METHOTREXATE 2.5 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures METHOTREXATE 2.5 MG TABLET?

METHOTREXATE 2.5 MG TABLET (NDC 62332073036) is labeled by Alembic Pharmaceuticals Inc., and CMS classifies it as a generic product.