Historical record - last NADAC effective date: 11/19/2014
This NDC is on FDA's drug shortage list (posted Mar 13, 2023)
Reported reason: Other
Product Information
METHOTREXATE 1 GRAM/40 ML VIAL is a generic product labeled by Teva Parenteral Medicines, Inc., priced at $0.6450 per ML under NDC 00703367801. Its NADAC has been published 100 times since Jan 22, 2014.
FDA first approved this application on Jan 11, 2010. Its Orange Book therapeutic-equivalence code is AP.
Strength
25 mg/mL
Manufacturer
Teva Parenteral Medicines, Inc.NDC
00703367801
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRA-ARTERIAL; INTRAMUSCULAR; INTRATHECAL; INTRAVENOUS
Effective Date
11/19/2014
Active Ingredients
METHOTREXATE SODIUMApproval Type
Generic (ANDA)
FDA Application
ANDA040843FDA Approved
1/11/2010
TE Code
AP
On Market Since
8/1/2012
Pharmacological Classes
Price Statistics
The NADAC for METHOTREXATE 1 GRAM/40 ML VIAL has been published 100 times since Jan 22, 2014, and over the history we have for it it has declined 29.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.6450 per ML |
|---|---|
| All-time high | $0.9146 (Nov 12, 2014) |
| All-time low | $0.6450 (Nov 19, 2014) |
| Median price | $0.6450 |
| Average price | $0.7609 |
| Largest weekly change | -29.5% (Nov 19, 2014) |
| Weeks tracked | 100 |
| Tracking since | Jan 22, 2014 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
N/A
5Y
N/A
All
-29.5%
Last surveyed Dec 16, 2015 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Teva Parenteral Medicines, Inc. manufacturer profile
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Drug market
Methotrexate market comparison
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Therapeutic class
Folate Analog Metabolic Inhibitor class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METHOTREXATE 1 GRAM/40 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 1 GRAM/40 ML VIAL, manufactured by Teva Parenteral Medicines, Inc., is $0.6450 per ML (NDC 00703367801), effective Dec 16, 2015.
How has the price of METHOTREXATE 1 GRAM/40 ML VIAL changed over time?
Over the history we have for it, the NADAC for METHOTREXATE 1 GRAM/40 ML VIAL has declined 29.5%. It has been tracked across 100 weekly CMS publications since Jan 22, 2014.
What are the highest and lowest recorded NADAC prices for METHOTREXATE 1 GRAM/40 ML VIAL?
Since Jan 22, 2014, the NADAC for METHOTREXATE 1 GRAM/40 ML VIAL has ranged from a low of $0.6450 (Nov 19, 2014) to a high of $0.9146 (Nov 12, 2014), with a median of $0.6450 per ML.
Are there cheaper alternatives to METHOTREXATE 1 GRAM/40 ML VIAL?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METHOTREXATE 1 GRAM/40 ML VIAL in a comparable dosage form, but none are currently priced below it.
Who manufactures METHOTREXATE 1 GRAM/40 ML VIAL?
METHOTREXATE 1 GRAM/40 ML VIAL (NDC 00703367801) is labeled by Teva Parenteral Medicines, Inc., and CMS classifies it as a generic product.
Is METHOTREXATE 1 GRAM/40 ML VIAL in shortage?
Yes — NDC 00703367801 is currently listed in FDA's drug shortage database (posted Mar 13, 2023). Reported reason: Other.