Product Information
METHOTREXATE 2.5 MG TABLET is a generic product labeled by Elite Laboratories, Inc., priced at $0.1577 per EA under NDC 64850033001. Its NADAC has been published 101 times since Oct 30, 2024.
FDA first approved this application on May 16, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2.5 mg/1
Manufacturer
Elite Laboratories, Inc.NDC
64850033001
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
METHOTREXATE SODIUMApproval Type
Generic (ANDA)
FDA Application
ANDA216453FDA Approved
5/16/2024
TE Code
AB
On Market Since
5/16/2024
Pharmacological Classes
Price Statistics
The NADAC for METHOTREXATE 2.5 MG TABLET has been published 101 times since Oct 30, 2024, and over the history we have for it it has declined 9.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1577 per EA |
|---|---|
| All-time high | $0.1741 (Nov 13, 2024) |
| All-time low | $0.1530 (Nov 19, 2025) |
| 52-week high | $0.1645 |
| 52-week low | $0.1530 |
| Median price | $0.1609 |
| Average price | $0.1608 |
| Largest weekly change | -7.0% (Nov 20, 2024) |
| Weeks tracked | 101 |
| Tracking since | Oct 30, 2024 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Elite Laboratories, Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Methotrexate Sodium market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Folate Analog Metabolic Inhibitor class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METHOTREXATE 2.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 2.5 MG TABLET, manufactured by Elite Laboratories, Inc., is $0.1577 per EA (NDC 64850033001), effective Sep 30, 2026.
How has the price of METHOTREXATE 2.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for METHOTREXATE 2.5 MG TABLET has declined 9.4%. It has been tracked across 101 weekly CMS publications since Oct 30, 2024.
What are the highest and lowest recorded NADAC prices for METHOTREXATE 2.5 MG TABLET?
Since Oct 30, 2024, the NADAC for METHOTREXATE 2.5 MG TABLET has ranged from a low of $0.1530 (Nov 19, 2025) to a high of $0.1741 (Nov 13, 2024), with a median of $0.1609 per EA.
Are there cheaper alternatives to METHOTREXATE 2.5 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METHOTREXATE 2.5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures METHOTREXATE 2.5 MG TABLET?
METHOTREXATE 2.5 MG TABLET (NDC 64850033001) is labeled by Elite Laboratories, Inc., and CMS classifies it as a generic product.