Product Information
METHOTREXATE 2.5 MG TABLET is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.1635 per EA under NDC 00378001401. Its NADAC has been published 657 times since Nov 28, 2013.
Strength
2.5 mg/1
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378001401
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
METHOTREXATE SODIUMApproval Type
Generic (ANDA)
FDA Application
ANDA081235On Market Since
5/18/1992
Pharmacological Classes
Price Statistics
The NADAC for METHOTREXATE 2.5 MG TABLET has been published 657 times since Nov 28, 2013, and over the history we have for it it has declined 92.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1635 per EA |
|---|---|
| All-time high | $2.2433 (Dec 11, 2013) |
| All-time low | $0.1507 (May 22, 2024) |
| 52-week high | $0.1694 |
| 52-week low | $0.1530 |
| Median price | $0.5327 |
| Average price | $0.7466 |
| Largest weekly change | +41.4% (Jun 19, 2024) |
| Weeks tracked | 657 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of METHOTREXATE 2.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 2.5 MG TABLET, manufactured by Mylan Pharmaceuticals Inc., is $0.1635 per EA (NDC 00378001401), effective Jun 24, 2026.
How has the price of METHOTREXATE 2.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for METHOTREXATE 2.5 MG TABLET has declined 92.7%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for METHOTREXATE 2.5 MG TABLET?
Since Nov 28, 2013, the NADAC for METHOTREXATE 2.5 MG TABLET has ranged from a low of $0.1507 (May 22, 2024) to a high of $2.2433 (Dec 11, 2013), with a median of $0.5327 per EA.
Are there cheaper alternatives to METHOTREXATE 2.5 MG TABLET?
1 NADAC-published product shares the same active ingredient, strength, and dosage form as METHOTREXATE 2.5 MG TABLET, but none are currently priced below it.
Who manufactures METHOTREXATE 2.5 MG TABLET?
METHOTREXATE 2.5 MG TABLET (NDC 00378001401) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.
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Same classification