Product Information
METHOTREXATE 2.5 MG TABLET is a generic product labeled by Sun Pharmaceutical Industries Inc., priced at $0.1577 per EA under NDC 47335023583. Its NADAC has been published 458 times since Dec 27, 2017.
FDA first approved this application on May 21, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2.5 mg/1
Manufacturer
Sun Pharmaceutical Industries Inc.NDC
47335023583
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
METHOTREXATE SODIUMApproval Type
Generic (ANDA)
FDA Application
ANDA201749FDA Approved
5/21/2015
TE Code
AB
On Market Since
11/10/2017
Pharmacological Classes
Price Statistics
The NADAC for METHOTREXATE 2.5 MG TABLET has been published 458 times since Dec 27, 2017, and over the history we have for it it has declined 81.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1577 per EA |
|---|---|
| All-time high | $0.9104 (Mar 14, 2018) |
| All-time low | $0.1507 (May 22, 2024) |
| 52-week high | $0.1645 |
| 52-week low | $0.1530 |
| Median price | $0.2699 |
| Average price | $0.3552 |
| Largest weekly change | +41.4% (Jun 19, 2024) |
| Weeks tracked | 458 |
| Tracking since | Dec 27, 2017 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Sun Pharmaceutical Industries Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Methotrexate Sodium market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Folate Analog Metabolic Inhibitor class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METHOTREXATE 2.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 2.5 MG TABLET, manufactured by Sun Pharmaceutical Industries Inc., is $0.1577 per EA (NDC 47335023583), effective Sep 30, 2026.
How has the price of METHOTREXATE 2.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for METHOTREXATE 2.5 MG TABLET has declined 81.6%. It has been tracked across 458 weekly CMS publications since Dec 27, 2017.
What are the highest and lowest recorded NADAC prices for METHOTREXATE 2.5 MG TABLET?
Since Dec 27, 2017, the NADAC for METHOTREXATE 2.5 MG TABLET has ranged from a low of $0.1507 (May 22, 2024) to a high of $0.9104 (Mar 14, 2018), with a median of $0.2699 per EA.
Are there cheaper alternatives to METHOTREXATE 2.5 MG TABLET?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METHOTREXATE 2.5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures METHOTREXATE 2.5 MG TABLET?
METHOTREXATE 2.5 MG TABLET (NDC 47335023583) is labeled by Sun Pharmaceutical Industries Inc., and CMS classifies it as a generic product.