Product Information

METHOTREXATE 2.5 MG TABLET is a generic product labeled by Sun Pharmaceutical Industries Inc., priced at $0.1566 per EA under NDC 47335023583. Its NADAC has been published 452 times since Dec 27, 2017.

FDA first approved this application on May 21, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METHOTREXATE 2.5 MG TABLET

Methotrexate Sodium
$0.1566per EA

Strength

2.5 mg/1

NDC

47335023583

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

METHOTREXATE SODIUM

Approval Type

Generic (ANDA)

FDA Application

ANDA201749

FDA Approved

5/21/2015

TE Code

AB

On Market Since

11/10/2017

Pharmacological Classes

Folate Analog Metabolic Inhibitor
Folic Acid Metabolism Inhibitors

Price Statistics

The NADAC for METHOTREXATE 2.5 MG TABLET has been published 452 times since Dec 27, 2017, and over the history we have for it it has declined 81.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1566 per EA
All-time high$0.9104 (Mar 14, 2018)
All-time low$0.1507 (May 22, 2024)
52-week high$0.1694
52-week low$0.1530
Median price$0.2715
Average price$0.3578
Largest weekly change+41.4% (Jun 19, 2024)
Weeks tracked452
Tracking sinceDec 27, 2017

Price History

1W

-1.1%

1M

-1.1%

3M

-4.6%

6M

-2.3%

1Y

-7.6%

3Y

-39.3%

5Y

-55.2%

All

-81.7%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METHOTREXATE 2.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 2.5 MG TABLET, manufactured by Sun Pharmaceutical Industries Inc., is $0.1566 per EA (NDC 47335023583), effective Aug 19, 2026.

How has the price of METHOTREXATE 2.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for METHOTREXATE 2.5 MG TABLET has declined 81.7%. It has been tracked across 452 weekly CMS publications since Dec 27, 2017.

What are the highest and lowest recorded NADAC prices for METHOTREXATE 2.5 MG TABLET?

Since Dec 27, 2017, the NADAC for METHOTREXATE 2.5 MG TABLET has ranged from a low of $0.1507 (May 22, 2024) to a high of $0.9104 (Mar 14, 2018), with a median of $0.2715 per EA.

Are there cheaper alternatives to METHOTREXATE 2.5 MG TABLET?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METHOTREXATE 2.5 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures METHOTREXATE 2.5 MG TABLET?

METHOTREXATE 2.5 MG TABLET (NDC 47335023583) is labeled by Sun Pharmaceutical Industries Inc., and CMS classifies it as a generic product.