Product Information
TRETINOIN 0.05% CREAM is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $0.9183 per GM under NDC 00378808345. Its NADAC has been published 381 times since Mar 13, 2019.
Strength
.5 mg/g
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378808345
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
TRETINOINApproval Type
Authorized Generic (NDA)
FDA Application
NDA017522On Market Since
11/5/2018
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.05% CREAM has been published 381 times since Mar 13, 2019, and over the history we have for it it has declined 66.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.9183 per GM |
|---|---|
| All-time high | $2.8260 (Jun 12, 2019) |
| All-time low | $0.9183 (Jun 17, 2026) |
| 52-week high | $1.4800 |
| 52-week low | $0.9183 |
| Median price | $1.7919 |
| Average price | $1.8797 |
| Largest weekly change | +31.2% (Jun 19, 2024) |
| Weeks tracked | 381 |
| Tracking since | Mar 13, 2019 |
Generic Alternatives
The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 14% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of TRETINOIN 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.05% CREAM, manufactured by Mylan Pharmaceuticals Inc., is $0.9183 per GM (NDC 00378808345), effective Jun 24, 2026.
How has the price of TRETINOIN 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.05% CREAM has declined 66.6%. It has been tracked across 381 weekly CMS publications since Mar 13, 2019.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.05% CREAM?
Since Mar 13, 2019, the NADAC for TRETINOIN 0.05% CREAM has ranged from a low of $0.9183 (Jun 17, 2026) to a high of $2.8260 (Jun 12, 2019), with a median of $1.7919 per GM.
Are there cheaper alternatives to TRETINOIN 0.05% CREAM?
Yes. 2 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, RETIN-A 0.05% CREAM, is $0.7904 per GM — about 14% below TRETINOIN 0.05% CREAM.
Who manufactures TRETINOIN 0.05% CREAM?
TRETINOIN 0.05% CREAM (NDC 00378808345) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.
Related Drugs
Same classification