Product Information
TRETINOIN 0.01% GEL is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $2.3019 per GM under NDC 00378808545. Its NADAC has been published 365 times since Oct 9, 2019.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.1 mg/g
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378808545
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
TRETINOINApproval Type
Authorized Generic (NDA)
FDA Application
NDA017955FDA Approved
Before 1982
TE Code
AB
On Market Since
8/12/2019
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.01% GEL has been published 365 times since Oct 9, 2019, and over the history we have for it it has declined 29.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.3019 per GM |
|---|---|
| All-time high | $3.3589 (Dec 15, 2021) |
| All-time low | $1.4922 (Nov 20, 2024) |
| 52-week high | $2.4280 |
| 52-week low | $2.1587 |
| Median price | $2.8007 |
| Average price | $2.7230 |
| Largest weekly change | -34.9% (Nov 20, 2024) |
| Weeks tracked | 365 |
| Tracking since | Oct 9, 2019 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 58% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Mylan Pharmaceuticals Inc. manufacturer profile
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Drug market
Tretinoin market comparison
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Therapeutic class
Retinoid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TRETINOIN 0.01% GEL?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.01% GEL, manufactured by Mylan Pharmaceuticals Inc., is $2.3019 per GM (NDC 00378808545), effective Sep 30, 2026.
How has the price of TRETINOIN 0.01% GEL changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.01% GEL has declined 29.3%. It has been tracked across 365 weekly CMS publications since Oct 9, 2019.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.01% GEL?
Since Oct 9, 2019, the NADAC for TRETINOIN 0.01% GEL has ranged from a low of $1.4922 (Nov 20, 2024) to a high of $3.3589 (Dec 15, 2021), with a median of $2.8007 per GM.
Are there cheaper alternatives to TRETINOIN 0.01% GEL?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, RETIN-A 0.01% GEL, is $0.9570 per GM — about 58% below TRETINOIN 0.01% GEL.
Who manufactures TRETINOIN 0.01% GEL?
TRETINOIN 0.01% GEL (NDC 00378808545) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.