Product Information
TRETINOIN 0.01% GEL is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $2.3076 per GM under NDC 00378808545. Its NADAC has been published 359 times since Oct 9, 2019.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.1 mg/g
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378808545
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
TRETINOINApproval Type
Authorized Generic (NDA)
FDA Application
NDA017955FDA Approved
Before 1982
TE Code
AB
On Market Since
8/12/2019
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.01% GEL has been published 359 times since Oct 9, 2019, and over the history we have for it it has declined 29.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.3076 per GM |
|---|---|
| All-time high | $3.3589 (Dec 15, 2021) |
| All-time low | $1.4922 (Nov 20, 2024) |
| 52-week high | $2.4992 |
| 52-week low | $2.1587 |
| Median price | $2.8400 |
| Average price | $2.7300 |
| Largest weekly change | -34.9% (Nov 20, 2024) |
| Weeks tracked | 359 |
| Tracking since | Oct 9, 2019 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 59% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TRETINOIN 0.01% GEL?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.01% GEL, manufactured by Mylan Pharmaceuticals Inc., is $2.3076 per GM (NDC 00378808545), effective Aug 19, 2026.
How has the price of TRETINOIN 0.01% GEL changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.01% GEL has declined 29.1%. It has been tracked across 359 weekly CMS publications since Oct 9, 2019.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.01% GEL?
Since Oct 9, 2019, the NADAC for TRETINOIN 0.01% GEL has ranged from a low of $1.4922 (Nov 20, 2024) to a high of $3.3589 (Dec 15, 2021), with a median of $2.8400 per GM.
Are there cheaper alternatives to TRETINOIN 0.01% GEL?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, RETIN-A 0.01% GEL, is $0.9570 per GM — about 59% below TRETINOIN 0.01% GEL.
Who manufactures TRETINOIN 0.01% GEL?
TRETINOIN 0.01% GEL (NDC 00378808545) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.