Product Information

TRETINOIN 0.025% GEL is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $2.5900 per GM under NDC 00378808645. Its NADAC has been published 351 times since Oct 9, 2019.

TRETINOIN 0.025% GEL

Tretinoin
$2.5900per GM

Strength

.25 mg/g

NDC

00378808645

Classification

Generic

Dosage Form

GEL

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

TRETINOIN

Approval Type

Authorized Generic (NDA)

FDA Application

NDA017579

On Market Since

7/12/2019

Pharmacological Classes

Retinoid
Retinoids

Price Statistics

The NADAC for TRETINOIN 0.025% GEL has been published 351 times since Oct 9, 2019, and over the history we have for it it has declined 22.4%. The table below summarizes its recorded NADAC range and movement.

Current price$2.5900 per GM
All-time high$3.3841 (May 13, 2020)
All-time low$1.7252 (Jul 17, 2024)
52-week high$2.5900
52-week low$2.3908
Median price$2.5309
Average price$2.5619
Largest weekly change-34.8% (Nov 20, 2024)
Weeks tracked351
Tracking sinceOct 9, 2019

Price History

1W

0.0%

1M

+0.8%

3M

+4.7%

6M

+2.0%

1Y

+4.1%

3Y

+9.3%

5Y

+5.0%

All

-22.4%

Generic Alternatives

The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 81% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of TRETINOIN 0.025% GEL?

The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.025% GEL, manufactured by Mylan Pharmaceuticals Inc., is $2.5900 per GM (NDC 00378808645), effective Jun 24, 2026.

How has the price of TRETINOIN 0.025% GEL changed over time?

Over the history we have for it, the NADAC for TRETINOIN 0.025% GEL has declined 22.4%. It has been tracked across 351 weekly CMS publications since Oct 9, 2019.

What are the highest and lowest recorded NADAC prices for TRETINOIN 0.025% GEL?

Since Oct 9, 2019, the NADAC for TRETINOIN 0.025% GEL has ranged from a low of $1.7252 (Jul 17, 2024) to a high of $3.3841 (May 13, 2020), with a median of $2.5309 per GM.

Are there cheaper alternatives to TRETINOIN 0.025% GEL?

Yes. 5 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, TRETINOIN 0.025% CREAM, is $0.4851 per GM — about 81% below TRETINOIN 0.025% GEL.

Who manufactures TRETINOIN 0.025% GEL?

TRETINOIN 0.025% GEL (NDC 00378808645) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.