Product Information
TRETINOIN 0.025% GEL is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $2.7073 per GM under NDC 00378808645. Its NADAC has been published 359 times since Oct 9, 2019.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.25 mg/g
Manufacturer
Mylan Pharmaceuticals Inc.NDC
00378808645
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
TRETINOINApproval Type
Authorized Generic (NDA)
FDA Application
NDA017579FDA Approved
Before 1982
TE Code
AB
On Market Since
7/12/2019
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.025% GEL has been published 359 times since Oct 9, 2019, and over the history we have for it it has declined 18.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.7073 per GM |
|---|---|
| All-time high | $3.3841 (May 13, 2020) |
| All-time low | $1.7252 (Jul 17, 2024) |
| 52-week high | $2.7073 |
| 52-week low | $2.3908 |
| Median price | $2.5309 |
| Average price | $2.5641 |
| Largest weekly change | -34.8% (Nov 20, 2024) |
| Weeks tracked | 359 |
| Tracking since | Oct 9, 2019 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TRETINOIN 0.025% GEL?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.025% GEL, manufactured by Mylan Pharmaceuticals Inc., is $2.7073 per GM (NDC 00378808645), effective Aug 19, 2026.
How has the price of TRETINOIN 0.025% GEL changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.025% GEL has declined 18.9%. It has been tracked across 359 weekly CMS publications since Oct 9, 2019.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.025% GEL?
Since Oct 9, 2019, the NADAC for TRETINOIN 0.025% GEL has ranged from a low of $1.7252 (Jul 17, 2024) to a high of $3.3841 (May 13, 2020), with a median of $2.5309 per GM.
Are there cheaper alternatives to TRETINOIN 0.025% GEL?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as TRETINOIN 0.025% GEL in a comparable dosage form, but none are currently priced below it.
Who manufactures TRETINOIN 0.025% GEL?
TRETINOIN 0.025% GEL (NDC 00378808645) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.