Product Information

EVAMIST 1.53 MG/SPRAY is a brand product labeled by Padagis US LLC, priced at $18.2160 per ML under NDC 00574206727. Its NADAC has been published 554 times since Nov 18, 2015.

EVAMIST 1.53 MG/SPRAY

Estradiol
$18.2160per ML

Strength

1.53 mg/1

Manufacturer

Padagis US LLC

NDC

00574206727

Classification

Brand

Dosage Form

SPRAY

Route

TRANSDERMAL

Last Updated

6/17/2026

Active Ingredients

ESTRADIOL

Approval Type

New Drug (NDA)

FDA Application

NDA022014

On Market Since

4/11/2015

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for EVAMIST 1.53 MG/SPRAY has been published 554 times since Nov 18, 2015, and over the history we have for it it has risen 41.7%. The table below summarizes its recorded NADAC range and movement.

Current price$18.2160 per ML
All-time high$18.2160 (Jun 24, 2026)
All-time low$12.8272 (Jan 20, 2016)
52-week high$18.2160
52-week low$17.3762
Median price$15.2323
Average price$15.3253
Largest weekly change+9.9% (Feb 15, 2023)
Weeks tracked554
Tracking sinceNov 18, 2015

Price History

1W

0.0%

1M

+0.4%

3M

+0.4%

6M

+4.8%

1Y

+4.4%

3Y

+8.5%

5Y

+19.5%

All

+41.7%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the Estradiol market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient, strength, and dosage form.

Frequently asked questions

What is the NADAC price of EVAMIST 1.53 MG/SPRAY?

The current National Average Drug Acquisition Cost (NADAC) for EVAMIST 1.53 MG/SPRAY, manufactured by Padagis US LLC, is $18.2160 per ML (NDC 00574206727), effective Jun 24, 2026.

How has the price of EVAMIST 1.53 MG/SPRAY changed over time?

Over the history we have for it, the NADAC for EVAMIST 1.53 MG/SPRAY has risen 41.7%. It has been tracked across 554 weekly CMS publications since Nov 18, 2015.

What are the highest and lowest recorded NADAC prices for EVAMIST 1.53 MG/SPRAY?

Since Nov 18, 2015, the NADAC for EVAMIST 1.53 MG/SPRAY has ranged from a low of $12.8272 (Jan 20, 2016) to a high of $18.2160 (Jun 24, 2026), with a median of $15.2323 per ML.

Are there cheaper alternatives to EVAMIST 1.53 MG/SPRAY?

No other NADAC-published product currently shares the active ingredient, strength, and dosage form of EVAMIST 1.53 MG/SPRAY, so no direct lower-cost alternative is listed.

Who manufactures EVAMIST 1.53 MG/SPRAY?

EVAMIST 1.53 MG/SPRAY (NDC 00574206727) is labeled by Padagis US LLC, and CMS classifies it as a brand product.