Product Information
EVAMIST 1.53 MG/SPRAY is a brand product labeled by Padagis US LLC, priced at $18.2666 per ML under NDC 00574206727. Its NADAC has been published 562 times since Nov 18, 2015.
FDA first approved this application on Jul 27, 2007.
Strength
1.53 mg/1
Manufacturer
Padagis US LLCNDC
00574206727
Classification
Brand
Dosage Form
SPRAY
Route
TRANSDERMAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA022014FDA Approved
7/27/2007
On Market Since
4/11/2015
Pharmacological Classes
Price Statistics
The NADAC for EVAMIST 1.53 MG/SPRAY has been published 562 times since Nov 18, 2015, and over the history we have for it it has risen 42.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $18.2666 per ML |
|---|---|
| All-time high | $18.2666 (Aug 19, 2026) |
| All-time low | $12.8272 (Jan 20, 2016) |
| 52-week high | $18.2666 |
| 52-week low | $17.3762 |
| Median price | $15.2391 |
| Average price | $15.3668 |
| Largest weekly change | +9.9% (Feb 15, 2023) |
| Weeks tracked | 562 |
| Tracking since | Nov 18, 2015 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Estradiol market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of EVAMIST 1.53 MG/SPRAY?
The current National Average Drug Acquisition Cost (NADAC) for EVAMIST 1.53 MG/SPRAY, manufactured by Padagis US LLC, is $18.2666 per ML (NDC 00574206727), effective Aug 19, 2026.
How has the price of EVAMIST 1.53 MG/SPRAY changed over time?
Over the history we have for it, the NADAC for EVAMIST 1.53 MG/SPRAY has risen 42.1%. It has been tracked across 562 weekly CMS publications since Nov 18, 2015.
What are the highest and lowest recorded NADAC prices for EVAMIST 1.53 MG/SPRAY?
Since Nov 18, 2015, the NADAC for EVAMIST 1.53 MG/SPRAY has ranged from a low of $12.8272 (Jan 20, 2016) to a high of $18.2666 (Aug 19, 2026), with a median of $15.2391 per ML.
Are there cheaper alternatives to EVAMIST 1.53 MG/SPRAY?
No other NADAC-published product currently shares the active ingredient and strength of EVAMIST 1.53 MG/SPRAY in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures EVAMIST 1.53 MG/SPRAY?
EVAMIST 1.53 MG/SPRAY (NDC 00574206727) is labeled by Padagis US LLC, and CMS classifies it as a brand product.