Product Information
EVAMIST 1.53 MG/SPRAY is a brand product labeled by Padagis US LLC, priced at $18.2194 per ML under NDC 00574206727. Its NADAC has been published 568 times since Nov 18, 2015.
FDA first approved this application on Jul 27, 2007.
Strength
1.53 mg/1
Manufacturer
Padagis US LLCNDC
00574206727
Classification
Brand
Dosage Form
SPRAY
Route
TRANSDERMAL
Effective Date
9/23/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA022014FDA Approved
7/27/2007
On Market Since
4/11/2015
Pharmacological Classes
Price Statistics
The NADAC for EVAMIST 1.53 MG/SPRAY has been published 568 times since Nov 18, 2015, and over the history we have for it it has risen 41.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $18.2194 per ML |
|---|---|
| All-time high | $18.2666 (Sep 16, 2026) |
| All-time low | $12.8272 (Jan 20, 2016) |
| 52-week high | $18.2666 |
| 52-week low | $17.3762 |
| Median price | $15.2391 |
| Average price | $15.3973 |
| Largest weekly change | +9.9% (Feb 15, 2023) |
| Weeks tracked | 568 |
| Tracking since | Nov 18, 2015 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Estradiol market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
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Manufacturer
Padagis US LLC manufacturer profile
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Drug market
Estradiol market comparison
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Therapeutic class
Estrogen class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of EVAMIST 1.53 MG/SPRAY?
The current National Average Drug Acquisition Cost (NADAC) for EVAMIST 1.53 MG/SPRAY, manufactured by Padagis US LLC, is $18.2194 per ML (NDC 00574206727), effective Sep 30, 2026.
How has the price of EVAMIST 1.53 MG/SPRAY changed over time?
Over the history we have for it, the NADAC for EVAMIST 1.53 MG/SPRAY has risen 41.7%. It has been tracked across 568 weekly CMS publications since Nov 18, 2015.
What are the highest and lowest recorded NADAC prices for EVAMIST 1.53 MG/SPRAY?
Since Nov 18, 2015, the NADAC for EVAMIST 1.53 MG/SPRAY has ranged from a low of $12.8272 (Jan 20, 2016) to a high of $18.2666 (Sep 16, 2026), with a median of $15.2391 per ML.
Are there cheaper alternatives to EVAMIST 1.53 MG/SPRAY?
No other NADAC-published product currently shares the active ingredient and strength of EVAMIST 1.53 MG/SPRAY in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures EVAMIST 1.53 MG/SPRAY?
EVAMIST 1.53 MG/SPRAY (NDC 00574206727) is labeled by Padagis US LLC, and CMS classifies it as a brand product.