Product Information
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.6628 per EA under NDC 00904701006. Its NADAC has been published 298 times since Jan 20, 2021.
FDA first approved this application on Jun 27, 2014. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET
buprenorphine hydrochloride and naloxone hydrochloride dihydrateStrength
8; 2 mg/1; mg/1
Manufacturer
Major PharmaceuticalsNDC
00904701006
Classification
Generic
Dosage Form
TABLET
Route
SUBLINGUAL
Effective Date
9/23/2026
Active Ingredients
BUPRENORPHINE HYDROCHLORIDE; NALOXONE HYDROCHLORIDE DIHYDRATEApproval Type
Generic (ANDA)
FDA Application
ANDA203326FDA Approved
6/27/2014
TE Code
AB
On Market Since
6/27/2014
Pharmacological Classes
Price Statistics
The NADAC for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET has been published 298 times since Jan 20, 2021, and over the history we have for it it has declined 44.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.6628 per EA |
|---|---|
| All-time high | $1.2290 (May 12, 2021) |
| All-time low | $0.6322 (Jul 22, 2026) |
| 52-week high | $0.7191 |
| 52-week low | $0.6322 |
| Median price | $0.9400 |
| Average price | $0.9061 |
| Largest weekly change | +29.6% (Aug 21, 2024) |
| Weeks tracked | 298 |
| Tracking since | Jan 20, 2021 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Major Pharmaceuticals manufacturer profile
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Drug market
buprenorphine hydrochloride and naloxone hydrochloride dihydrate market comparison
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Therapeutic class
Opioid Antagonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET, manufactured by Major Pharmaceuticals, is $0.6628 per EA (NDC 00904701006), effective Sep 30, 2026.
How has the price of BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET changed over time?
Over the history we have for it, the NADAC for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET has declined 44.0%. It has been tracked across 298 weekly CMS publications since Jan 20, 2021.
What are the highest and lowest recorded NADAC prices for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
Since Jan 20, 2021, the NADAC for BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET has ranged from a low of $0.6322 (Jul 22, 2026) to a high of $1.2290 (May 12, 2021), with a median of $0.9400 per EA.
Are there cheaper alternatives to BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET?
BUPRENORPHINE-NALOXONE 8-2 MG SL TABLET (NDC 00904701006) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.