Product Information
METHOTREXATE 50 MG/2 ML VIAL is a generic product labeled by Accord Healthcare Inc., priced at $1.7390 per ML under NDC 16729027730. Its NADAC has been published 634 times since May 7, 2014.
Strength
25 mg/mL
Manufacturer
Accord Healthcare Inc.NDC
16729027730
Classification
Generic
Dosage Form
INJECTION
Route
INTRA-ARTERIAL; INTRAMUSCULAR; INTRATHECAL; INTRAVENOUS
Last Updated
6/17/2026
Active Ingredients
METHOTREXATEApproval Type
Generic (ANDA)
FDA Application
ANDA040716On Market Since
3/7/2014
Pharmacological Classes
Price Statistics
The NADAC for METHOTREXATE 50 MG/2 ML VIAL has been published 634 times since May 7, 2014, and over the history we have for it it has declined 11.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.7390 per ML |
|---|---|
| All-time high | $3.1936 (Mar 11, 2020) |
| All-time low | $1.2092 (Aug 23, 2017) |
| 52-week high | $2.4419 |
| 52-week low | $1.5600 |
| Median price | $1.6538 |
| Average price | $1.8590 |
| Largest weekly change | +53.6% (Jan 23, 2019) |
| Weeks tracked | 634 |
| Tracking since | May 7, 2014 |
Generic Alternatives
The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 63% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of METHOTREXATE 50 MG/2 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 50 MG/2 ML VIAL, manufactured by Accord Healthcare Inc., is $1.7390 per ML (NDC 16729027730), effective Jun 24, 2026.
How has the price of METHOTREXATE 50 MG/2 ML VIAL changed over time?
Over the history we have for it, the NADAC for METHOTREXATE 50 MG/2 ML VIAL has declined 11.0%. It has been tracked across 634 weekly CMS publications since May 7, 2014.
What are the highest and lowest recorded NADAC prices for METHOTREXATE 50 MG/2 ML VIAL?
Since May 7, 2014, the NADAC for METHOTREXATE 50 MG/2 ML VIAL has ranged from a low of $1.2092 (Aug 23, 2017) to a high of $3.1936 (Mar 11, 2020), with a median of $1.6538 per ML.
Are there cheaper alternatives to METHOTREXATE 50 MG/2 ML VIAL?
Yes. 4 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, METHOTREXATE 1 GRAM/40 ML VIAL, is $0.6450 per ML — about 63% below METHOTREXATE 50 MG/2 ML VIAL.
Who manufactures METHOTREXATE 50 MG/2 ML VIAL?
METHOTREXATE 50 MG/2 ML VIAL (NDC 16729027730) is labeled by Accord Healthcare Inc., and CMS classifies it as a generic product.
Related Drugs
Same classification