Product Information
METHOTREXATE 50 MG/2 ML VIAL is a generic product labeled by Hospira Inc., priced at $3.2634 per ML under NDC 61703016105. Its NADAC has been published 76 times since Jan 15, 2025.
Strength
25 mg/mL
Manufacturer
Hospira Inc.NDC
61703016105
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRATHECAL; INTRAVENOUS; SUBCUTANEOUS
Last Updated
6/17/2026
Active Ingredients
METHOTREXATE SODIUMApproval Type
New Drug (NDA)
FDA Application
NDA011719On Market Since
11/4/2024
Pharmacological Classes
Price Statistics
The NADAC for METHOTREXATE 50 MG/2 ML VIAL has been published 76 times since Jan 15, 2025, and over the history we have for it it has risen 5.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.2634 per ML |
|---|---|
| All-time high | $3.3602 (Jun 10, 2026) |
| All-time low | $2.9679 (Jun 18, 2025) |
| 52-week high | $3.3602 |
| 52-week low | $2.9679 |
| Median price | $3.1788 |
| Average price | $3.1792 |
| Largest weekly change | +4.1% (Sep 17, 2025) |
| Weeks tracked | 76 |
| Tracking since | Jan 15, 2025 |
Generic Alternatives
The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 80% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of METHOTREXATE 50 MG/2 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 50 MG/2 ML VIAL, manufactured by Hospira Inc., is $3.2634 per ML (NDC 61703016105), effective Jun 24, 2026.
How has the price of METHOTREXATE 50 MG/2 ML VIAL changed over time?
Over the history we have for it, the NADAC for METHOTREXATE 50 MG/2 ML VIAL has risen 5.4%. It has been tracked across 76 weekly CMS publications since Jan 15, 2025.
What are the highest and lowest recorded NADAC prices for METHOTREXATE 50 MG/2 ML VIAL?
Since Jan 15, 2025, the NADAC for METHOTREXATE 50 MG/2 ML VIAL has ranged from a low of $2.9679 (Jun 18, 2025) to a high of $3.3602 (Jun 10, 2026), with a median of $3.1788 per ML.
Are there cheaper alternatives to METHOTREXATE 50 MG/2 ML VIAL?
Yes. 4 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, METHOTREXATE 1 GRAM/40 ML VIAL, is $0.6450 per ML — about 80% below METHOTREXATE 50 MG/2 ML VIAL.
Who manufactures METHOTREXATE 50 MG/2 ML VIAL?
METHOTREXATE 50 MG/2 ML VIAL (NDC 61703016105) is labeled by Hospira Inc., and CMS classifies it as a generic product.
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