Product Information
DOTTI 0.0375 MG PATCH is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $7.8091 per EA under NDC 65162099208. Its NADAC has been published 364 times since Jul 10, 2019.
Strength
.0375 mg/d
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162099208
Classification
Generic
Dosage Form
PATCH, EXTENDED RELEASE
Route
TRANSDERMAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA211293On Market Since
2/4/2019
Pharmacological Classes
Price Statistics
The NADAC for DOTTI 0.0375 MG PATCH has been published 364 times since Jul 10, 2019, and over the history we have for it it has declined 8.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $7.8091 per EA |
|---|---|
| All-time high | $10.3341 (Apr 13, 2022) |
| All-time low | $5.3236 (Nov 20, 2024) |
| 52-week high | $7.8091 |
| 52-week low | $6.6398 |
| Median price | $7.0982 |
| Average price | $7.2995 |
| Largest weekly change | +29.5% (Mar 23, 2022) |
| Weeks tracked | 364 |
| Tracking since | Jul 10, 2019 |
Generic Alternatives
The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of DOTTI 0.0375 MG PATCH?
The current National Average Drug Acquisition Cost (NADAC) for DOTTI 0.0375 MG PATCH, manufactured by Amneal Pharmaceuticals LLC, is $7.8091 per EA (NDC 65162099208), effective Jun 24, 2026.
How has the price of DOTTI 0.0375 MG PATCH changed over time?
Over the history we have for it, the NADAC for DOTTI 0.0375 MG PATCH has declined 8.3%. It has been tracked across 364 weekly CMS publications since Jul 10, 2019.
What are the highest and lowest recorded NADAC prices for DOTTI 0.0375 MG PATCH?
Since Jul 10, 2019, the NADAC for DOTTI 0.0375 MG PATCH has ranged from a low of $5.3236 (Nov 20, 2024) to a high of $10.3341 (Apr 13, 2022), with a median of $7.0982 per EA.
Are there cheaper alternatives to DOTTI 0.0375 MG PATCH?
4 NADAC-published products share the same active ingredient, strength, and dosage form as DOTTI 0.0375 MG PATCH, but none are currently priced below it.
Who manufactures DOTTI 0.0375 MG PATCH?
DOTTI 0.0375 MG PATCH (NDC 65162099208) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.
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