Product Information
TRETINOIN 0.025% CREAM is a generic product labeled by Alembic Pharmaceuticals Inc., priced at $0.4684 per GM under NDC 62332080945. Its NADAC has been published 38 times since Dec 3, 2025.
FDA first approved this application on Aug 14, 2025. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.25 mg/g
Manufacturer
Alembic Pharmaceuticals Inc.NDC
62332080945
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA218399FDA Approved
8/14/2025
TE Code
AB
On Market Since
8/16/2025
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.025% CREAM has been published 38 times since Dec 3, 2025, and over the history we have for it it has declined 52.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4684 per GM |
|---|---|
| All-time high | $0.9756 (Dec 10, 2025) |
| All-time low | $0.4684 (Aug 19, 2026) |
| 52-week high | $0.9756 |
| 52-week low | $0.4684 |
| Median price | $0.7970 |
| Average price | $0.7274 |
| Largest weekly change | -19.3% (May 20, 2026) |
| Weeks tracked | 38 |
| Tracking since | Dec 3, 2025 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TRETINOIN 0.025% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.025% CREAM, manufactured by Alembic Pharmaceuticals Inc., is $0.4684 per GM (NDC 62332080945), effective Aug 19, 2026.
How has the price of TRETINOIN 0.025% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.025% CREAM has declined 52.0%. It has been tracked across 38 weekly CMS publications since Dec 3, 2025.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.025% CREAM?
Since Dec 3, 2025, the NADAC for TRETINOIN 0.025% CREAM has ranged from a low of $0.4684 (Aug 19, 2026) to a high of $0.9756 (Dec 10, 2025), with a median of $0.7970 per GM.
Are there cheaper alternatives to TRETINOIN 0.025% CREAM?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TRETINOIN 0.025% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures TRETINOIN 0.025% CREAM?
TRETINOIN 0.025% CREAM (NDC 62332080945) is labeled by Alembic Pharmaceuticals Inc., and CMS classifies it as a generic product.