Product Information
METHOTREXATE 2.5 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.1635 per EA under NDC 00904714110. Its NADAC has been published 254 times since Aug 18, 2021.
Strength
2.5 mg/1
Manufacturer
Major PharmaceuticalsNDC
00904714110
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
METHOTREXATEApproval Type
Generic (ANDA)
FDA Application
ANDA207812On Market Since
2/9/2017
Pharmacological Classes
Price Statistics
The NADAC for METHOTREXATE 2.5 MG TABLET has been published 254 times since Aug 18, 2021, and over the history we have for it it has declined 53.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1635 per EA |
|---|---|
| All-time high | $0.3498 (Sep 15, 2021) |
| All-time low | $0.1507 (May 22, 2024) |
| 52-week high | $0.1694 |
| 52-week low | $0.1530 |
| Median price | $0.1846 |
| Average price | $0.2074 |
| Largest weekly change | +41.4% (Jun 19, 2024) |
| Weeks tracked | 254 |
| Tracking since | Aug 18, 2021 |
Generic Alternatives
The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of METHOTREXATE 2.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 2.5 MG TABLET, manufactured by Major Pharmaceuticals, is $0.1635 per EA (NDC 00904714110), effective Jun 24, 2026.
How has the price of METHOTREXATE 2.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for METHOTREXATE 2.5 MG TABLET has declined 53.3%. It has been tracked across 254 weekly CMS publications since Aug 18, 2021.
What are the highest and lowest recorded NADAC prices for METHOTREXATE 2.5 MG TABLET?
Since Aug 18, 2021, the NADAC for METHOTREXATE 2.5 MG TABLET has ranged from a low of $0.1507 (May 22, 2024) to a high of $0.3498 (Sep 15, 2021), with a median of $0.1846 per EA.
Are there cheaper alternatives to METHOTREXATE 2.5 MG TABLET?
5 NADAC-published products share the same active ingredient, strength, and dosage form as METHOTREXATE 2.5 MG TABLET, but none are currently priced below it.
Who manufactures METHOTREXATE 2.5 MG TABLET?
METHOTREXATE 2.5 MG TABLET (NDC 00904714110) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.
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