Product Information
METHOTREXATE 2.5 MG TABLET is a generic product labeled by Accord Healthcare Inc., priced at $0.1635 per EA under NDC 16729048601. Its NADAC has been published 298 times since Oct 14, 2020.
Strength
2.5 mg/1
Manufacturer
Accord Healthcare Inc.NDC
16729048601
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
METHOTREXATE SODIUMApproval Type
Generic (ANDA)
FDA Application
ANDA213343On Market Since
8/24/2020
Pharmacological Classes
Price Statistics
The NADAC for METHOTREXATE 2.5 MG TABLET has been published 298 times since Oct 14, 2020, and over the history we have for it it has declined 59.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1635 per EA |
|---|---|
| All-time high | $0.5061 (Mar 10, 2021) |
| All-time low | $0.1507 (May 22, 2024) |
| 52-week high | $0.1694 |
| 52-week low | $0.1530 |
| Median price | $0.2100 |
| Average price | $0.2388 |
| Largest weekly change | +41.4% (Jun 19, 2024) |
| Weeks tracked | 298 |
| Tracking since | Oct 14, 2020 |
Generic Alternatives
The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of METHOTREXATE 2.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 2.5 MG TABLET, manufactured by Accord Healthcare Inc., is $0.1635 per EA (NDC 16729048601), effective Jun 24, 2026.
How has the price of METHOTREXATE 2.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for METHOTREXATE 2.5 MG TABLET has declined 59.5%. It has been tracked across 298 weekly CMS publications since Oct 14, 2020.
What are the highest and lowest recorded NADAC prices for METHOTREXATE 2.5 MG TABLET?
Since Oct 14, 2020, the NADAC for METHOTREXATE 2.5 MG TABLET has ranged from a low of $0.1507 (May 22, 2024) to a high of $0.5061 (Mar 10, 2021), with a median of $0.2100 per EA.
Are there cheaper alternatives to METHOTREXATE 2.5 MG TABLET?
5 NADAC-published products share the same active ingredient, strength, and dosage form as METHOTREXATE 2.5 MG TABLET, but none are currently priced below it.
Who manufactures METHOTREXATE 2.5 MG TABLET?
METHOTREXATE 2.5 MG TABLET (NDC 16729048601) is labeled by Accord Healthcare Inc., and CMS classifies it as a generic product.
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