Product Information

METHOTREXATE 2.5 MG TABLET is a generic product labeled by Aurobindo Pharma Limited, priced at $0.1635 per EA under NDC 59651018201. Its NADAC has been published 307 times since Aug 12, 2020.

METHOTREXATE 2.5 MG TABLET

Methotrexate
$0.1635per EA

Strength

2.5 mg/1

NDC

59651018201

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

METHOTREXATE SODIUM

Approval Type

Generic (ANDA)

FDA Application

ANDA210454

On Market Since

1/30/2020

Pharmacological Classes

Folate Analog Metabolic Inhibitor
Folic Acid Metabolism Inhibitors

Price Statistics

The NADAC for METHOTREXATE 2.5 MG TABLET has been published 307 times since Aug 12, 2020, and over the history we have for it it has declined 59.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1635 per EA
All-time high$0.5061 (Mar 10, 2021)
All-time low$0.1507 (May 22, 2024)
52-week high$0.1694
52-week low$0.1530
Median price$0.2126
Average price$0.2441
Largest weekly change+41.4% (Jun 19, 2024)
Weeks tracked307
Tracking sinceAug 12, 2020

Price History

1W

0.0%

1M

-0.4%

3M

+3.1%

6M

+3.4%

1Y

-0.2%

3Y

-40.4%

5Y

-46.3%

All

-59.7%

Generic Alternatives

The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METHOTREXATE 2.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 2.5 MG TABLET, manufactured by Aurobindo Pharma Limited, is $0.1635 per EA (NDC 59651018201), effective Jun 24, 2026.

How has the price of METHOTREXATE 2.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for METHOTREXATE 2.5 MG TABLET has declined 59.7%. It has been tracked across 307 weekly CMS publications since Aug 12, 2020.

What are the highest and lowest recorded NADAC prices for METHOTREXATE 2.5 MG TABLET?

Since Aug 12, 2020, the NADAC for METHOTREXATE 2.5 MG TABLET has ranged from a low of $0.1507 (May 22, 2024) to a high of $0.5061 (Mar 10, 2021), with a median of $0.2126 per EA.

Are there cheaper alternatives to METHOTREXATE 2.5 MG TABLET?

5 NADAC-published products share the same active ingredient, strength, and dosage form as METHOTREXATE 2.5 MG TABLET, but none are currently priced below it.

Who manufactures METHOTREXATE 2.5 MG TABLET?

METHOTREXATE 2.5 MG TABLET (NDC 59651018201) is labeled by Aurobindo Pharma Limited, and CMS classifies it as a generic product.