Product Information
METHOTREXATE 2.5 MG TABLET is a generic product labeled by Aurobindo Pharma Limited, priced at $0.1566 per EA under NDC 59651018201. Its NADAC has been published 315 times since Aug 12, 2020.
FDA first approved this application on Jan 30, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2.5 mg/1
Manufacturer
Aurobindo Pharma LimitedNDC
59651018201
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METHOTREXATE SODIUMApproval Type
Generic (ANDA)
FDA Application
ANDA210454FDA Approved
1/30/2020
TE Code
AB
On Market Since
1/30/2020
Pharmacological Classes
Price Statistics
The NADAC for METHOTREXATE 2.5 MG TABLET has been published 315 times since Aug 12, 2020, and over the history we have for it it has declined 61.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1566 per EA |
|---|---|
| All-time high | $0.5061 (Mar 10, 2021) |
| All-time low | $0.1507 (May 22, 2024) |
| 52-week high | $0.1694 |
| 52-week low | $0.1530 |
| Median price | $0.2100 |
| Average price | $0.2420 |
| Largest weekly change | +41.4% (Jun 19, 2024) |
| Weeks tracked | 315 |
| Tracking since | Aug 12, 2020 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METHOTREXATE 2.5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 2.5 MG TABLET, manufactured by Aurobindo Pharma Limited, is $0.1566 per EA (NDC 59651018201), effective Aug 19, 2026.
How has the price of METHOTREXATE 2.5 MG TABLET changed over time?
Over the history we have for it, the NADAC for METHOTREXATE 2.5 MG TABLET has declined 61.4%. It has been tracked across 315 weekly CMS publications since Aug 12, 2020.
What are the highest and lowest recorded NADAC prices for METHOTREXATE 2.5 MG TABLET?
Since Aug 12, 2020, the NADAC for METHOTREXATE 2.5 MG TABLET has ranged from a low of $0.1507 (May 22, 2024) to a high of $0.5061 (Mar 10, 2021), with a median of $0.2100 per EA.
Are there cheaper alternatives to METHOTREXATE 2.5 MG TABLET?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as METHOTREXATE 2.5 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures METHOTREXATE 2.5 MG TABLET?
METHOTREXATE 2.5 MG TABLET (NDC 59651018201) is labeled by Aurobindo Pharma Limited, and CMS classifies it as a generic product.