Product Information

NALOXONE HCL 4 MG NASAL SPRAY is a generic product labeled by Teva Pharmaceuticals USA Inc., priced at $16.9224 per EA under NDC 00480347868. Its NADAC has been published 96 times since Oct 23, 2024.

FDA first approved this application on Apr 19, 2019.

NALOXONE HCL 4 MG NASAL SPRAY

Naloxone Hydrochloride
$16.9224per EA
OTC

Strength

4 mg/.1mL

NDC

00480347868

Classification

Generic

Dosage Form

SPRAY, METERED

Route

NASAL

Effective Date

8/19/2026

Active Ingredients

NALOXONE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA209522

FDA Approved

4/19/2019

On Market Since

9/23/2024

Pharmacological Classes

Opioid Antagonist
Opioid Antagonists

Price Statistics

The NADAC for NALOXONE HCL 4 MG NASAL SPRAY has been published 96 times since Oct 23, 2024, and over the history we have for it it has declined 46.3%. The table below summarizes its recorded NADAC range and movement.

Current price$16.9224 per EA
All-time high$31.5147 (Nov 13, 2024)
All-time low$15.2248 (May 20, 2026)
52-week high$23.1012
52-week low$15.2248
Median price$22.8128
Average price$22.0233
Largest weekly change-32.4% (Nov 19, 2025)
Weeks tracked96
Tracking sinceOct 23, 2024

Price History

1W

+6.6%

1M

+6.6%

3M

+11.2%

6M

+9.7%

1Y

-26.7%

3Y

N/A

5Y

N/A

All

-46.3%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of NALOXONE HCL 4 MG NASAL SPRAY?

The current National Average Drug Acquisition Cost (NADAC) for NALOXONE HCL 4 MG NASAL SPRAY, manufactured by Teva Pharmaceuticals USA Inc., is $16.9224 per EA (NDC 00480347868), effective Aug 19, 2026.

How has the price of NALOXONE HCL 4 MG NASAL SPRAY changed over time?

Over the history we have for it, the NADAC for NALOXONE HCL 4 MG NASAL SPRAY has declined 46.3%. It has been tracked across 96 weekly CMS publications since Oct 23, 2024.

What are the highest and lowest recorded NADAC prices for NALOXONE HCL 4 MG NASAL SPRAY?

Since Oct 23, 2024, the NADAC for NALOXONE HCL 4 MG NASAL SPRAY has ranged from a low of $15.2248 (May 20, 2026) to a high of $31.5147 (Nov 13, 2024), with a median of $22.8128 per EA.

Are there cheaper alternatives to NALOXONE HCL 4 MG NASAL SPRAY?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as NALOXONE HCL 4 MG NASAL SPRAY in a comparable dosage form, but none are currently priced below it.

Who manufactures NALOXONE HCL 4 MG NASAL SPRAY?

NALOXONE HCL 4 MG NASAL SPRAY (NDC 00480347868) is labeled by Teva Pharmaceuticals USA Inc., and CMS classifies it as a generic product.