Product Information
TRETINOIN 0.05% CREAM is a generic product labeled by Padagis US LLC, priced at $0.9183 per GM under NDC 00574220545. Its NADAC has been published 475 times since May 24, 2017.
Strength
.5 mg/g
Manufacturer
Padagis US LLCNDC
00574220545
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA075265On Market Since
4/26/2017
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.05% CREAM has been published 475 times since May 24, 2017, and over the history we have for it it has declined 72.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.9183 per GM |
|---|---|
| All-time high | $3.5935 (Jul 12, 2017) |
| All-time low | $0.9183 (Jun 17, 2026) |
| 52-week high | $1.4800 |
| 52-week low | $0.9183 |
| Median price | $2.1198 |
| Average price | $2.1295 |
| Largest weekly change | +31.2% (Jun 19, 2024) |
| Weeks tracked | 475 |
| Tracking since | May 24, 2017 |
Generic Alternatives
The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of TRETINOIN 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.05% CREAM, manufactured by Padagis US LLC, is $0.9183 per GM (NDC 00574220545), effective Jun 24, 2026.
How has the price of TRETINOIN 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.05% CREAM has declined 72.2%. It has been tracked across 475 weekly CMS publications since May 24, 2017.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.05% CREAM?
Since May 24, 2017, the NADAC for TRETINOIN 0.05% CREAM has ranged from a low of $0.9183 (Jun 17, 2026) to a high of $3.5935 (Jul 12, 2017), with a median of $2.1198 per GM.
Are there cheaper alternatives to TRETINOIN 0.05% CREAM?
4 NADAC-published products share the same active ingredient, strength, and dosage form as TRETINOIN 0.05% CREAM, but none are currently priced below it.
Who manufactures TRETINOIN 0.05% CREAM?
TRETINOIN 0.05% CREAM (NDC 00574220545) is labeled by Padagis US LLC, and CMS classifies it as a generic product.
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Same classification