Product Information
TRETINOIN 0.05% CREAM is a generic product labeled by Sun Pharmaceutical Industries Inc., priced at $1.0505 per GM under NDC 51672139409. Its NADAC has been published 392 times since Apr 3, 2019.
FDA first approved this application on Jan 25, 2019. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/g
Manufacturer
Sun Pharmaceutical Industries Inc.NDC
51672139409
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA211644FDA Approved
1/25/2019
TE Code
AB1
On Market Since
1/25/2019
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.05% CREAM has been published 392 times since Apr 3, 2019, and over the history we have for it it has declined 57.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0505 per GM |
|---|---|
| All-time high | $2.8260 (Jun 12, 2019) |
| All-time low | $0.9063 (Jul 22, 2026) |
| 52-week high | $1.3122 |
| 52-week low | $0.9063 |
| Median price | $1.7811 |
| Average price | $1.8408 |
| Largest weekly change | +31.2% (Jun 19, 2024) |
| Weeks tracked | 392 |
| Tracking since | Apr 3, 2019 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Sun Pharmaceutical Industries Inc. manufacturer profile
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Drug market
tretinoin market comparison
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Therapeutic class
Retinoid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TRETINOIN 0.05% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.05% CREAM, manufactured by Sun Pharmaceutical Industries Inc., is $1.0505 per GM (NDC 51672139409), effective Sep 30, 2026.
How has the price of TRETINOIN 0.05% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.05% CREAM has declined 57.5%. It has been tracked across 392 weekly CMS publications since Apr 3, 2019.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.05% CREAM?
Since Apr 3, 2019, the NADAC for TRETINOIN 0.05% CREAM has ranged from a low of $0.9063 (Jul 22, 2026) to a high of $2.8260 (Jun 12, 2019), with a median of $1.7811 per GM.
Are there cheaper alternatives to TRETINOIN 0.05% CREAM?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TRETINOIN 0.05% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures TRETINOIN 0.05% CREAM?
TRETINOIN 0.05% CREAM (NDC 51672139409) is labeled by Sun Pharmaceutical Industries Inc., and CMS classifies it as a generic product.