Product Information
TRETINOIN 0.025% CREAM is a generic product labeled by Padagis US LLC, priced at $0.5720 per GM under NDC 00574222520. Its NADAC has been published 455 times since Oct 11, 2017.
Strength
.25 mg/g
Manufacturer
Padagis US LLCNDC
00574222520
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA075264On Market Since
6/15/2017
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.025% CREAM has been published 455 times since Oct 11, 2017, and over the history we have for it it has declined 81.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5720 per GM |
|---|---|
| All-time high | $3.3664 (Sep 12, 2018) |
| All-time low | $0.5720 (Jun 17, 2026) |
| 52-week high | $1.0981 |
| 52-week low | $0.5720 |
| Median price | $2.0691 |
| Average price | $1.8496 |
| Largest weekly change | +51.5% (Oct 21, 2020) |
| Weeks tracked | 455 |
| Tracking since | Oct 11, 2017 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 15% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of TRETINOIN 0.025% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.025% CREAM, manufactured by Padagis US LLC, is $0.5720 per GM (NDC 00574222520), effective Jun 24, 2026.
How has the price of TRETINOIN 0.025% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.025% CREAM has declined 81.2%. It has been tracked across 455 weekly CMS publications since Oct 11, 2017.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.025% CREAM?
Since Oct 11, 2017, the NADAC for TRETINOIN 0.025% CREAM has ranged from a low of $0.5720 (Jun 17, 2026) to a high of $3.3664 (Sep 12, 2018), with a median of $2.0691 per GM.
Are there cheaper alternatives to TRETINOIN 0.025% CREAM?
Yes. 3 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, TRETINOIN 0.025% CREAM, is $0.4851 per GM — about 15% below TRETINOIN 0.025% CREAM.
Who manufactures TRETINOIN 0.025% CREAM?
TRETINOIN 0.025% CREAM (NDC 00574222520) is labeled by Padagis US LLC, and CMS classifies it as a generic product.
Related Drugs
Same classification