Product Information

ISOTRETINOIN 40 MG CAPSULE is a generic product labeled by Actavis Pharma, Inc., priced at $5.3067 per EA under NDC 00591243615. Its NADAC has been published 267 times since May 19, 2021.

ISOTRETINOIN 40 MG CAPSULE

Isotretinoin
$5.3067per EA

Strength

40 mg/1

NDC

00591243615

Classification

Generic

Dosage Form

CAPSULE

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

ISOTRETINOIN

Approval Type

Generic (ANDA)

FDA Application

ANDA205063

On Market Since

4/29/2021

Pharmacological Classes

Retinoid
Retinoids

Price Statistics

The NADAC for ISOTRETINOIN 40 MG CAPSULE has been published 267 times since May 19, 2021, and over the history we have for it it has risen 54.4%. The table below summarizes its recorded NADAC range and movement.

Current price$5.3067 per EA
All-time high$26.7665 (Jun 15, 2022)
All-time low$3.0414 (Jun 23, 2021)
52-week high$15.9249
52-week low$5.0999
Median price$15.8056
Average price$16.7805
Largest weekly change+780.1% (Jul 21, 2021)
Weeks tracked267
Tracking sinceMay 19, 2021

Price History

1W

0.0%

1M

+4.1%

3M

-26.3%

6M

-63.2%

1Y

-59.2%

3Y

-69.7%

5Y

+74.5%

All

+54.4%

Generic Alternatives

The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 59% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ISOTRETINOIN 40 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for ISOTRETINOIN 40 MG CAPSULE, manufactured by Actavis Pharma, Inc., is $5.3067 per EA (NDC 00591243615), effective Jun 24, 2026.

How has the price of ISOTRETINOIN 40 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for ISOTRETINOIN 40 MG CAPSULE has risen 54.4%. It has been tracked across 267 weekly CMS publications since May 19, 2021.

What are the highest and lowest recorded NADAC prices for ISOTRETINOIN 40 MG CAPSULE?

Since May 19, 2021, the NADAC for ISOTRETINOIN 40 MG CAPSULE has ranged from a low of $3.0414 (Jun 23, 2021) to a high of $26.7665 (Jun 15, 2022), with a median of $15.8056 per EA.

Are there cheaper alternatives to ISOTRETINOIN 40 MG CAPSULE?

Yes. 6 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, ISOTRETINOIN 40 MG CAPSULE, is $2.1672 per EA — about 59% below ISOTRETINOIN 40 MG CAPSULE.

Who manufactures ISOTRETINOIN 40 MG CAPSULE?

ISOTRETINOIN 40 MG CAPSULE (NDC 00591243615) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.