Product Information
ISOTRETINOIN 40 MG CAPSULE is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $2.1849 per EA under NDC 70710102508. Its NADAC has been published 144 times since Nov 22, 2023.
FDA first approved this application on Aug 29, 2023. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
40 mg/1
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
70710102508
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ISOTRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA211568FDA Approved
8/29/2023
TE Code
AB1
On Market Since
9/12/2023
Pharmacological Classes
Price Statistics
The NADAC for ISOTRETINOIN 40 MG CAPSULE has been published 144 times since Nov 22, 2023, and over the history we have for it it has declined 18.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.1849 per EA |
|---|---|
| All-time high | $2.8206 (Apr 10, 2024) |
| All-time low | $1.9456 (Nov 20, 2024) |
| 52-week high | $2.4672 |
| 52-week low | $2.0775 |
| Median price | $2.3894 |
| Average price | $2.3664 |
| Largest weekly change | +28.0% (Aug 21, 2024) |
| Weeks tracked | 144 |
| Tracking since | Nov 22, 2023 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ISOTRETINOIN 40 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for ISOTRETINOIN 40 MG CAPSULE, manufactured by Zydus Pharmaceuticals (USA) Inc., is $2.1849 per EA (NDC 70710102508), effective Aug 19, 2026.
How has the price of ISOTRETINOIN 40 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for ISOTRETINOIN 40 MG CAPSULE has declined 18.6%. It has been tracked across 144 weekly CMS publications since Nov 22, 2023.
What are the highest and lowest recorded NADAC prices for ISOTRETINOIN 40 MG CAPSULE?
Since Nov 22, 2023, the NADAC for ISOTRETINOIN 40 MG CAPSULE has ranged from a low of $1.9456 (Nov 20, 2024) to a high of $2.8206 (Apr 10, 2024), with a median of $2.3894 per EA.
Are there cheaper alternatives to ISOTRETINOIN 40 MG CAPSULE?
6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ISOTRETINOIN 40 MG CAPSULE in a comparable dosage form, but none are currently priced below it.
Who manufactures ISOTRETINOIN 40 MG CAPSULE?
ISOTRETINOIN 40 MG CAPSULE (NDC 70710102508) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.