Product Information
ISOTRETINOIN 40 MG CAPSULE is a generic product labeled by Mayne Pharma, priced at $2.1672 per EA under NDC 68308078430. Its NADAC has been published 125 times since Feb 7, 2024.
Strength
40 mg/1
Manufacturer
Mayne PharmaNDC
68308078430
Classification
Generic
Dosage Form
CAPSULE, LIQUID FILLED
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
ISOTRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA076485On Market Since
5/1/2012
Pharmacological Classes
Price Statistics
The NADAC for ISOTRETINOIN 40 MG CAPSULE has been published 125 times since Feb 7, 2024, and over the history we have for it it has declined 22.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.1672 per EA |
|---|---|
| All-time high | $2.8206 (Apr 10, 2024) |
| All-time low | $1.9456 (Nov 20, 2024) |
| 52-week high | $2.4672 |
| 52-week low | $2.0775 |
| Median price | $2.3759 |
| Average price | $2.3493 |
| Largest weekly change | +28.0% (Aug 21, 2024) |
| Weeks tracked | 125 |
| Tracking since | Feb 7, 2024 |
Generic Alternatives
The matcher finds 7 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 7 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of ISOTRETINOIN 40 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for ISOTRETINOIN 40 MG CAPSULE, manufactured by Mayne Pharma, is $2.1672 per EA (NDC 68308078430), effective Jun 24, 2026.
How has the price of ISOTRETINOIN 40 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for ISOTRETINOIN 40 MG CAPSULE has declined 22.5%. It has been tracked across 125 weekly CMS publications since Feb 7, 2024.
What are the highest and lowest recorded NADAC prices for ISOTRETINOIN 40 MG CAPSULE?
Since Feb 7, 2024, the NADAC for ISOTRETINOIN 40 MG CAPSULE has ranged from a low of $1.9456 (Nov 20, 2024) to a high of $2.8206 (Apr 10, 2024), with a median of $2.3759 per EA.
Are there cheaper alternatives to ISOTRETINOIN 40 MG CAPSULE?
7 NADAC-published products share the same active ingredient, strength, and dosage form as ISOTRETINOIN 40 MG CAPSULE, but none are currently priced below it.
Who manufactures ISOTRETINOIN 40 MG CAPSULE?
ISOTRETINOIN 40 MG CAPSULE (NDC 68308078430) is labeled by Mayne Pharma, and CMS classifies it as a generic product.
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