Product Information
ISOTRETINOIN 40 MG CAPSULE is a generic product labeled by Amneal Pharmaceuticals NY LLC, priced at $2.1849 per EA under NDC 69238117603. Its NADAC has been published 443 times since Feb 28, 2018.
FDA first approved this application on Sep 29, 2017. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
40 mg/1
Manufacturer
Amneal Pharmaceuticals NY LLCNDC
69238117603
Classification
Generic
Dosage Form
CAPSULE, LIQUID FILLED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ISOTRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA207792FDA Approved
9/29/2017
TE Code
AB1
On Market Since
10/2/2017
Pharmacological Classes
Price Statistics
The NADAC for ISOTRETINOIN 40 MG CAPSULE has been published 443 times since Feb 28, 2018, and over the history we have for it it has declined 57.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.1849 per EA |
|---|---|
| All-time high | $5.1559 (Mar 14, 2018) |
| All-time low | $1.9456 (Nov 20, 2024) |
| 52-week high | $2.4672 |
| 52-week low | $2.0775 |
| Median price | $2.9916 |
| Average price | $2.9732 |
| Largest weekly change | +28.0% (Aug 21, 2024) |
| Weeks tracked | 443 |
| Tracking since | Feb 28, 2018 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ISOTRETINOIN 40 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for ISOTRETINOIN 40 MG CAPSULE, manufactured by Amneal Pharmaceuticals NY LLC, is $2.1849 per EA (NDC 69238117603), effective Aug 19, 2026.
How has the price of ISOTRETINOIN 40 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for ISOTRETINOIN 40 MG CAPSULE has declined 57.6%. It has been tracked across 443 weekly CMS publications since Feb 28, 2018.
What are the highest and lowest recorded NADAC prices for ISOTRETINOIN 40 MG CAPSULE?
Since Feb 28, 2018, the NADAC for ISOTRETINOIN 40 MG CAPSULE has ranged from a low of $1.9456 (Nov 20, 2024) to a high of $5.1559 (Mar 14, 2018), with a median of $2.9916 per EA.
Are there cheaper alternatives to ISOTRETINOIN 40 MG CAPSULE?
6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ISOTRETINOIN 40 MG CAPSULE in a comparable dosage form, but none are currently priced below it.
Who manufactures ISOTRETINOIN 40 MG CAPSULE?
ISOTRETINOIN 40 MG CAPSULE (NDC 69238117603) is labeled by Amneal Pharmaceuticals NY LLC, and CMS classifies it as a generic product.