Product Information

METHOTREXATE 250 MG/10 ML VIAL is a generic product labeled by Teva Parenteral Medicines, Inc., priced at $0.7327 per ML under NDC 00703367501. Its NADAC has been published 470 times since Nov 28, 2013.

METHOTREXATE 250 MG/10 ML VIAL

Methotrexate
$0.7327per ML

Strength

25 mg/mL

NDC

00703367501

Classification

Generic

Dosage Form

INJECTION, SOLUTION

Route

INTRA-ARTERIAL; INTRAMUSCULAR; INTRATHECAL; INTRAVENOUS

Last Updated

6/17/2026

Active Ingredients

METHOTREXATE SODIUM

Approval Type

Generic (ANDA)

FDA Application

ANDA040843

On Market Since

8/1/2012

Pharmacological Classes

Folate Analog Metabolic Inhibitor
Folic Acid Metabolism Inhibitors

Price Statistics

The NADAC for METHOTREXATE 250 MG/10 ML VIAL has been published 470 times since Nov 28, 2013, and over the history we have for it it has declined 50.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.7327 per ML
All-time high$1.4874 (Dec 11, 2013)
All-time low$0.6670 (Sep 21, 2016)
52-week high$0.8206
52-week low$0.7082
Median price$0.7998
Average price$0.7864
Largest weekly change-45.7% (Dec 18, 2013)
Weeks tracked470
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

-3.6%

3M

-8.7%

6M

+3.5%

1Y

-0.7%

3Y

+7.1%

5Y

-8.4%

All

-50.7%

Generic Alternatives

The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 12% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METHOTREXATE 250 MG/10 ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 250 MG/10 ML VIAL, manufactured by Teva Parenteral Medicines, Inc., is $0.7327 per ML (NDC 00703367501), effective Jun 24, 2026.

How has the price of METHOTREXATE 250 MG/10 ML VIAL changed over time?

Over the history we have for it, the NADAC for METHOTREXATE 250 MG/10 ML VIAL has declined 50.7%. It has been tracked across 470 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for METHOTREXATE 250 MG/10 ML VIAL?

Since Nov 28, 2013, the NADAC for METHOTREXATE 250 MG/10 ML VIAL has ranged from a low of $0.6670 (Sep 21, 2016) to a high of $1.4874 (Dec 11, 2013), with a median of $0.7998 per ML.

Are there cheaper alternatives to METHOTREXATE 250 MG/10 ML VIAL?

Yes. 4 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, METHOTREXATE 1 GRAM/40 ML VIAL, is $0.6450 per ML — about 12% below METHOTREXATE 250 MG/10 ML VIAL.

Who manufactures METHOTREXATE 250 MG/10 ML VIAL?

METHOTREXATE 250 MG/10 ML VIAL (NDC 00703367501) is labeled by Teva Parenteral Medicines, Inc., and CMS classifies it as a generic product.