Historical record - last NADAC effective date: 7/17/2024
Product Information
METHOTREXATE 250 MG/10 ML VIAL is a generic product labeled by Accord Healthcare Inc., priced at $0.8029 per ML under NDC 16729027703. Its NADAC has been published 350 times since May 7, 2014.
FDA first approved this application on Apr 30, 2007. Its Orange Book therapeutic-equivalence code is AP.
Strength
25 mg/mL
Manufacturer
Accord Healthcare Inc.NDC
16729027703
Classification
Generic
Dosage Form
INJECTION
Route
INTRA-ARTERIAL; INTRAMUSCULAR; INTRATHECAL; INTRAVENOUS
Effective Date
7/17/2024
Active Ingredients
METHOTREXATEApproval Type
Generic (ANDA)
FDA Application
ANDA040716FDA Approved
4/30/2007
TE Code
AP
On Market Since
3/7/2014
Pharmacological Classes
Price Statistics
The NADAC for METHOTREXATE 250 MG/10 ML VIAL has been published 350 times since May 7, 2014, and over the history we have for it it has declined 6.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.8029 per ML |
|---|---|
| All-time high | $1.1148 (Jul 15, 2015) |
| All-time low | $0.6670 (Sep 21, 2016) |
| Median price | $0.7998 |
| Average price | $0.7827 |
| Largest weekly change | +42.2% (Jun 22, 2016) |
| Weeks tracked | 350 |
| Tracking since | May 7, 2014 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
+17.3%
5Y
+0.4%
All
-6.0%
Last surveyed Aug 14, 2024 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 20% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METHOTREXATE 250 MG/10 ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 250 MG/10 ML VIAL, manufactured by Accord Healthcare Inc., is $0.8029 per ML (NDC 16729027703), effective Aug 14, 2024.
How has the price of METHOTREXATE 250 MG/10 ML VIAL changed over time?
Over the history we have for it, the NADAC for METHOTREXATE 250 MG/10 ML VIAL has declined 6.0%. It has been tracked across 350 weekly CMS publications since May 7, 2014.
What are the highest and lowest recorded NADAC prices for METHOTREXATE 250 MG/10 ML VIAL?
Since May 7, 2014, the NADAC for METHOTREXATE 250 MG/10 ML VIAL has ranged from a low of $0.6670 (Sep 21, 2016) to a high of $1.1148 (Jul 15, 2015), with a median of $0.7998 per ML.
Are there cheaper alternatives to METHOTREXATE 250 MG/10 ML VIAL?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METHOTREXATE 1 GRAM/40 ML VIAL, is $0.6450 per ML — about 20% below METHOTREXATE 250 MG/10 ML VIAL.
Who manufactures METHOTREXATE 250 MG/10 ML VIAL?
METHOTREXATE 250 MG/10 ML VIAL (NDC 16729027703) is labeled by Accord Healthcare Inc., and CMS classifies it as a generic product.