Product Information
TRETINOIN 0.01% GEL is a generic product labeled by Encube Ethicals, Inc., priced at $3.4518 per GM under NDC 21922005604. Its NADAC has been published 44 times since Aug 27, 2025.
Strength
.1 mg/g
Manufacturer
Encube Ethicals, Inc.NDC
21922005604
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA217588On Market Since
3/6/2025
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.01% GEL has been published 44 times since Aug 27, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.4518 per GM |
|---|---|
| All-time high | $3.5061 (Feb 11, 2026) |
| All-time low | $3.3200 (Sep 17, 2025) |
| 52-week high | $3.5061 |
| 52-week low | $3.3200 |
| Median price | $3.4092 |
| Average price | $3.4096 |
| Largest weekly change | +4.9% (May 20, 2026) |
| Weeks tracked | 44 |
| Tracking since | Aug 27, 2025 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 72% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of TRETINOIN 0.01% GEL?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.01% GEL, manufactured by Encube Ethicals, Inc., is $3.4518 per GM (NDC 21922005604), effective Jun 24, 2026.
How has the price of TRETINOIN 0.01% GEL changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.01% GEL has held within roughly two percent of its current level. It has been tracked across 44 weekly CMS publications since Aug 27, 2025.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.01% GEL?
Since Aug 27, 2025, the NADAC for TRETINOIN 0.01% GEL has ranged from a low of $3.3200 (Sep 17, 2025) to a high of $3.5061 (Feb 11, 2026), with a median of $3.4092 per GM.
Are there cheaper alternatives to TRETINOIN 0.01% GEL?
Yes. 3 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, RETIN-A 0.01% GEL, is $0.9570 per GM — about 72% below TRETINOIN 0.01% GEL.
Who manufactures TRETINOIN 0.01% GEL?
TRETINOIN 0.01% GEL (NDC 21922005604) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.
Related Drugs
Same classification