Product Information

NALOXONE 0.4 MG/ML VIAL is a generic product labeled by Baxter Healthcare Corporation, priced at $4.0147 per ML under NDC 36000030810. Its NADAC has been published 175 times since Jul 20, 2022.

FDA first approved this application on Jan 29, 2021. Its Orange Book therapeutic-equivalence code is AP.

NALOXONE 0.4 MG/ML VIAL

naloxone hydrochloride
$4.0147per ML

Strength

.4 mg/mL

NDC

36000030810

Classification

Generic

Dosage Form

INJECTION, SOLUTION

Route

INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS

Effective Date

8/19/2026

Active Ingredients

NALOXONE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA214785

FDA Approved

1/29/2021

TE Code

AP

On Market Since

1/29/2021

Pharmacological Classes

Opioid Antagonist
Opioid Antagonists

Price Statistics

The NADAC for NALOXONE 0.4 MG/ML VIAL has been published 175 times since Jul 20, 2022, and over the history we have for it it has declined 38.1%. The table below summarizes its recorded NADAC range and movement.

Current price$4.0147 per ML
All-time high$8.0996 (Aug 14, 2024)
All-time low$3.8172 (Dec 17, 2025)
52-week high$5.3047
52-week low$3.8172
Median price$6.3000
Average price$5.7574
Largest weekly change+24.9% (May 22, 2024)
Weeks tracked175
Tracking sinceJul 20, 2022

Price History

1W

-5.1%

1M

-5.1%

3M

-8.3%

6M

+1.6%

1Y

-24.3%

3Y

-38.1%

5Y

N/A

All

-38.1%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of NALOXONE 0.4 MG/ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for NALOXONE 0.4 MG/ML VIAL, manufactured by Baxter Healthcare Corporation, is $4.0147 per ML (NDC 36000030810), effective Aug 19, 2026.

How has the price of NALOXONE 0.4 MG/ML VIAL changed over time?

Over the history we have for it, the NADAC for NALOXONE 0.4 MG/ML VIAL has declined 38.1%. It has been tracked across 175 weekly CMS publications since Jul 20, 2022.

What are the highest and lowest recorded NADAC prices for NALOXONE 0.4 MG/ML VIAL?

Since Jul 20, 2022, the NADAC for NALOXONE 0.4 MG/ML VIAL has ranged from a low of $3.8172 (Dec 17, 2025) to a high of $8.0996 (Aug 14, 2024), with a median of $6.3000 per ML.

Are there cheaper alternatives to NALOXONE 0.4 MG/ML VIAL?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as NALOXONE 0.4 MG/ML VIAL in a comparable dosage form, but none are currently priced below it.

Who manufactures NALOXONE 0.4 MG/ML VIAL?

NALOXONE 0.4 MG/ML VIAL (NDC 36000030810) is labeled by Baxter Healthcare Corporation, and CMS classifies it as a generic product.