Product Information
NALOXONE 0.4 MG/ML VIAL is a generic product labeled by NorthStar Rx LLC, priced at $4.0147 per ML under NDC 72603059010. Its NADAC has been published 86 times since Jan 1, 2025.
FDA first approved this application on Feb 29, 2024. Its Orange Book therapeutic-equivalence code is AP.
Strength
.4 mg/mL
Manufacturer
NorthStar Rx LLCNDC
72603059010
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS
Effective Date
8/19/2026
Active Ingredients
NALOXONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA218404FDA Approved
2/29/2024
TE Code
AP
On Market Since
7/1/2024
Pharmacological Classes
Price Statistics
The NADAC for NALOXONE 0.4 MG/ML VIAL has been published 86 times since Jan 1, 2025, and over the history we have for it it has declined 37.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $4.0147 per ML |
|---|---|
| All-time high | $6.4146 (Jan 15, 2025) |
| All-time low | $3.8172 (Dec 17, 2025) |
| 52-week high | $5.3047 |
| 52-week low | $3.8172 |
| Median price | $4.4135 |
| Average price | $4.6883 |
| Largest weekly change | -13.1% (Oct 22, 2025) |
| Weeks tracked | 86 |
| Tracking since | Jan 1, 2025 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of NALOXONE 0.4 MG/ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for NALOXONE 0.4 MG/ML VIAL, manufactured by NorthStar Rx LLC, is $4.0147 per ML (NDC 72603059010), effective Aug 19, 2026.
How has the price of NALOXONE 0.4 MG/ML VIAL changed over time?
Over the history we have for it, the NADAC for NALOXONE 0.4 MG/ML VIAL has declined 37.4%. It has been tracked across 86 weekly CMS publications since Jan 1, 2025.
What are the highest and lowest recorded NADAC prices for NALOXONE 0.4 MG/ML VIAL?
Since Jan 1, 2025, the NADAC for NALOXONE 0.4 MG/ML VIAL has ranged from a low of $3.8172 (Dec 17, 2025) to a high of $6.4146 (Jan 15, 2025), with a median of $4.4135 per ML.
Are there cheaper alternatives to NALOXONE 0.4 MG/ML VIAL?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as NALOXONE 0.4 MG/ML VIAL in a comparable dosage form, but none are currently priced below it.
Who manufactures NALOXONE 0.4 MG/ML VIAL?
NALOXONE 0.4 MG/ML VIAL (NDC 72603059010) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.