Product Information

BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $0.4123 per EA under NDC 65162041603. Its NADAC has been published 657 times since Nov 28, 2013.

BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET

Buprenorphine and Naloxone
$0.4123per EA
DEA Schedule CIII

Strength

2; .5 mg/1; mg/1

NDC

65162041603

Classification

Generic

Dosage Form

TABLET

Route

SUBLINGUAL

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA203136

On Market Since

2/22/2013

Pharmacological Classes

Opioid Antagonist
Opioid Antagonists
Partial Opioid Agonist
Partial Opioid Agonists

Price Statistics

The NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET has been published 657 times since Nov 28, 2013, and over the history we have for it it has declined 88.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.4123 per EA
All-time high$3.7455 (Aug 13, 2014)
All-time low$0.3740 (Nov 20, 2024)
52-week high$0.5463
52-week low$0.4123
Median price$1.1091
Average price$1.7238
Largest weekly change+58.5% (Aug 21, 2024)
Weeks tracked657
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

-4.4%

3M

-14.3%

6M

-13.0%

1Y

-20.9%

3Y

-32.5%

5Y

-52.3%

All

-88.9%

Generic Alternatives

The matcher finds 9 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 9 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET, manufactured by Amneal Pharmaceuticals LLC, is $0.4123 per EA (NDC 65162041603), effective Jun 24, 2026.

How has the price of BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET changed over time?

Over the history we have for it, the NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET has declined 88.9%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?

Since Nov 28, 2013, the NADAC for BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET has ranged from a low of $0.3740 (Nov 20, 2024) to a high of $3.7455 (Aug 13, 2014), with a median of $1.1091 per EA.

Are there cheaper alternatives to BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?

9 NADAC-published products share the same active ingredient, strength, and dosage form as BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET, but none are currently priced below it.

Who manufactures BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET?

BUPRENORPHINE-NALOXONE 2-0.5 MG SL TABLET (NDC 65162041603) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.