Product Information
NALOXONE HCL 4 MG NASAL SPRAY is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $15.4599 per EA under NDC 45802057884. Its NADAC has been published 123 times since Feb 21, 2024.
Strength
4 mg/.1mL
Manufacturer
Padagis Israel Pharmaceuticals LtdNDC
45802057884
Classification
Generic
Dosage Form
SPRAY
Route
NASAL
Last Updated
6/17/2026
Active Ingredients
NALOXONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA211951On Market Since
7/30/2023
Pharmacological Classes
Price Statistics
The NADAC for NALOXONE HCL 4 MG NASAL SPRAY has been published 123 times since Feb 21, 2024, and over the history we have for it it has declined 41.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $15.4599 per EA |
|---|---|
| All-time high | $38.8039 (Jul 10, 2024) |
| All-time low | $15.2248 (May 20, 2026) |
| 52-week high | $26.2968 |
| 52-week low | $15.2248 |
| Median price | $26.2968 |
| Average price | $25.6277 |
| Largest weekly change | +49.1% (Jun 19, 2024) |
| Weeks tracked | 123 |
| Tracking since | Feb 21, 2024 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of NALOXONE HCL 4 MG NASAL SPRAY?
The current National Average Drug Acquisition Cost (NADAC) for NALOXONE HCL 4 MG NASAL SPRAY, manufactured by Padagis Israel Pharmaceuticals Ltd, is $15.4599 per EA (NDC 45802057884), effective Jun 24, 2026.
How has the price of NALOXONE HCL 4 MG NASAL SPRAY changed over time?
Over the history we have for it, the NADAC for NALOXONE HCL 4 MG NASAL SPRAY has declined 41.6%. It has been tracked across 123 weekly CMS publications since Feb 21, 2024.
What are the highest and lowest recorded NADAC prices for NALOXONE HCL 4 MG NASAL SPRAY?
Since Feb 21, 2024, the NADAC for NALOXONE HCL 4 MG NASAL SPRAY has ranged from a low of $15.2248 (May 20, 2026) to a high of $38.8039 (Jul 10, 2024), with a median of $26.2968 per EA.
Are there cheaper alternatives to NALOXONE HCL 4 MG NASAL SPRAY?
3 NADAC-published products share the same active ingredient, strength, and dosage form as NALOXONE HCL 4 MG NASAL SPRAY, but none are currently priced below it.
Who manufactures NALOXONE HCL 4 MG NASAL SPRAY?
NALOXONE HCL 4 MG NASAL SPRAY (NDC 45802057884) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.
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Same classification