Product Information

NALOXONE HCL 4 MG NASAL SPRAY is a generic product labeled by BluePoint Laboratories, priced at $16.9224 per EA under NDC 68001064545. Its NADAC has been published 63 times since Jun 11, 2025.

FDA first approved this application on Jun 21, 2022.

NALOXONE HCL 4 MG NASAL SPRAY

naloxone hydrochloride
$16.9224per EA
OTC

Strength

4 mg/.1mL

NDC

68001064545

Classification

Generic

Dosage Form

SPRAY

Route

NASAL

Effective Date

8/19/2026

Active Ingredients

NALOXONE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA211951

FDA Approved

6/21/2022

On Market Since

5/1/2025

Pharmacological Classes

Opioid Antagonist
Opioid Antagonists

Price Statistics

The NADAC for NALOXONE HCL 4 MG NASAL SPRAY has been published 63 times since Jun 11, 2025, and over the history we have for it it has declined 39.3%. The table below summarizes its recorded NADAC range and movement.

Current price$16.9224 per EA
All-time high$27.8591 (Jun 11, 2025)
All-time low$15.2248 (May 20, 2026)
52-week high$23.1012
52-week low$15.2248
Median price$15.6988
Average price$18.7265
Largest weekly change-32.4% (Nov 19, 2025)
Weeks tracked63
Tracking sinceJun 11, 2025

Price History

1W

+6.6%

1M

+6.6%

3M

+11.2%

6M

+9.7%

1Y

-26.7%

3Y

N/A

5Y

N/A

All

-39.3%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of NALOXONE HCL 4 MG NASAL SPRAY?

The current National Average Drug Acquisition Cost (NADAC) for NALOXONE HCL 4 MG NASAL SPRAY, manufactured by BluePoint Laboratories, is $16.9224 per EA (NDC 68001064545), effective Aug 19, 2026.

How has the price of NALOXONE HCL 4 MG NASAL SPRAY changed over time?

Over the history we have for it, the NADAC for NALOXONE HCL 4 MG NASAL SPRAY has declined 39.3%. It has been tracked across 63 weekly CMS publications since Jun 11, 2025.

What are the highest and lowest recorded NADAC prices for NALOXONE HCL 4 MG NASAL SPRAY?

Since Jun 11, 2025, the NADAC for NALOXONE HCL 4 MG NASAL SPRAY has ranged from a low of $15.2248 (May 20, 2026) to a high of $27.8591 (Jun 11, 2025), with a median of $15.6988 per EA.

Are there cheaper alternatives to NALOXONE HCL 4 MG NASAL SPRAY?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as NALOXONE HCL 4 MG NASAL SPRAY in a comparable dosage form, but none are currently priced below it.

Who manufactures NALOXONE HCL 4 MG NASAL SPRAY?

NALOXONE HCL 4 MG NASAL SPRAY (NDC 68001064545) is labeled by BluePoint Laboratories, and CMS classifies it as a generic product.