Product Information
ISOTRETINOIN 25 MG CAPSULE is a generic product labeled by Sun Pharmaceutical Industries Inc., priced at $10.5512 per EA under NDC 57664002297. Its NADAC has been published 129 times since Apr 17, 2024.
FDA first approved this application on May 25, 2012. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Isotretinoin market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
25 mg/1
Manufacturer
Sun Pharmaceutical Industries Inc.NDC
57664002297
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ISOTRETINOINApproval Type
Authorized Generic (NDA)
FDA Application
NDA021951FDA Approved
5/25/2012
TE Code
AB2
On Market Since
12/29/2020
Pharmacological Classes
Price Statistics
The NADAC for ISOTRETINOIN 25 MG CAPSULE has been published 129 times since Apr 17, 2024, and over the history we have for it it has declined 37.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $10.5512 per EA |
|---|---|
| All-time high | $17.3949 (Jan 15, 2025) |
| All-time low | $10.4672 (May 20, 2026) |
| 52-week high | $10.9483 |
| 52-week low | $10.4672 |
| Median price | $11.2115 |
| Average price | $13.4209 |
| Largest weekly change | -13.2% (Apr 23, 2025) |
| Weeks tracked | 129 |
| Tracking since | Apr 17, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Sun Pharmaceutical Industries Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Isotretinoin market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Retinoid class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ISOTRETINOIN 25 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for ISOTRETINOIN 25 MG CAPSULE, manufactured by Sun Pharmaceutical Industries Inc., is $10.5512 per EA (NDC 57664002297), effective Sep 30, 2026.
How has the price of ISOTRETINOIN 25 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for ISOTRETINOIN 25 MG CAPSULE has declined 37.9%. It has been tracked across 129 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for ISOTRETINOIN 25 MG CAPSULE?
Since Apr 17, 2024, the NADAC for ISOTRETINOIN 25 MG CAPSULE has ranged from a low of $10.4672 (May 20, 2026) to a high of $17.3949 (Jan 15, 2025), with a median of $11.2115 per EA.
Are there cheaper alternatives to ISOTRETINOIN 25 MG CAPSULE?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as ISOTRETINOIN 25 MG CAPSULE in a comparable dosage form, but none are currently priced below it.
Who manufactures ISOTRETINOIN 25 MG CAPSULE?
ISOTRETINOIN 25 MG CAPSULE (NDC 57664002297) is labeled by Sun Pharmaceutical Industries Inc., and CMS classifies it as a generic product.