Product Information

METHOTREXATE 50 MG/2 ML VIAL is a generic product labeled by Hospira Inc., priced at $3.2634 per ML under NDC 61703035010. Its NADAC has been published 316 times since Jun 10, 2020.

METHOTREXATE 50 MG/2 ML VIAL

Methotrexate
$3.2634per ML

Strength

25 mg/mL

Manufacturer

Hospira Inc.

NDC

61703035010

Classification

Generic

Dosage Form

INJECTION, SOLUTION

Route

INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS

Last Updated

6/17/2026

Active Ingredients

METHOTREXATE SODIUM

Approval Type

New Drug (NDA)

FDA Application

NDA011719

On Market Since

9/25/2014

Pharmacological Classes

Folate Analog Metabolic Inhibitor
Folic Acid Metabolism Inhibitors

Price Statistics

The NADAC for METHOTREXATE 50 MG/2 ML VIAL has been published 316 times since Jun 10, 2020, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.

Current price$3.2634 per ML
All-time high$3.4029 (Feb 16, 2022)
All-time low$2.6573 (Jul 17, 2024)
52-week high$3.3602
52-week low$2.9679
Median price$3.1788
Average price$3.1631
Largest weekly change-20.7% (Jul 17, 2024)
Weeks tracked316
Tracking sinceJun 10, 2020

Price History

1W

0.0%

1M

-2.9%

3M

-2.8%

6M

+0.1%

1Y

+10.0%

3Y

+8.1%

5Y

+4.5%

All

-1.9%

Generic Alternatives

The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 80% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METHOTREXATE 50 MG/2 ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 50 MG/2 ML VIAL, manufactured by Hospira Inc., is $3.2634 per ML (NDC 61703035010), effective Jun 24, 2026.

How has the price of METHOTREXATE 50 MG/2 ML VIAL changed over time?

Over the history we have for it, the NADAC for METHOTREXATE 50 MG/2 ML VIAL has held within roughly two percent of its current level. It has been tracked across 316 weekly CMS publications since Jun 10, 2020.

What are the highest and lowest recorded NADAC prices for METHOTREXATE 50 MG/2 ML VIAL?

Since Jun 10, 2020, the NADAC for METHOTREXATE 50 MG/2 ML VIAL has ranged from a low of $2.6573 (Jul 17, 2024) to a high of $3.4029 (Feb 16, 2022), with a median of $3.1788 per ML.

Are there cheaper alternatives to METHOTREXATE 50 MG/2 ML VIAL?

Yes. 4 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, METHOTREXATE 1 GRAM/40 ML VIAL, is $0.6450 per ML — about 80% below METHOTREXATE 50 MG/2 ML VIAL.

Who manufactures METHOTREXATE 50 MG/2 ML VIAL?

METHOTREXATE 50 MG/2 ML VIAL (NDC 61703035010) is labeled by Hospira Inc., and CMS classifies it as a generic product.