Product Information

METHOTREXATE 50 MG/2 ML VIAL is a generic product labeled by Hospira Inc., priced at $3.2634 per ML under NDC 61703035038. Its NADAC has been published 657 times since Nov 28, 2013.

METHOTREXATE 50 MG/2 ML VIAL

Methotrexate
$3.2634per ML

Strength

25 mg/mL

Manufacturer

Hospira Inc.

NDC

61703035038

Classification

Generic

Dosage Form

INJECTION, SOLUTION

Route

INTRAMUSCULAR; INTRAVENOUS; SUBCUTANEOUS

Last Updated

6/17/2026

Active Ingredients

METHOTREXATE SODIUM

Approval Type

New Drug (NDA)

FDA Application

NDA011719

On Market Since

9/25/2014

Pharmacological Classes

Folate Analog Metabolic Inhibitor
Folic Acid Metabolism Inhibitors

Price Statistics

The NADAC for METHOTREXATE 50 MG/2 ML VIAL has been published 657 times since Nov 28, 2013, and over the history we have for it it has risen 32.0%. The table below summarizes its recorded NADAC range and movement.

Current price$3.2634 per ML
All-time high$3.5278 (Jul 15, 2015)
All-time low$2.4714 (Nov 28, 2013)
52-week high$3.3602
52-week low$2.9679
Median price$3.1986
Average price$3.1753
Largest weekly change-20.7% (Jul 17, 2024)
Weeks tracked657
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

-2.9%

3M

-2.8%

6M

+0.1%

1Y

+10.0%

3Y

+8.1%

5Y

+4.5%

All

+32.0%

Generic Alternatives

The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 80% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METHOTREXATE 50 MG/2 ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for METHOTREXATE 50 MG/2 ML VIAL, manufactured by Hospira Inc., is $3.2634 per ML (NDC 61703035038), effective Jun 24, 2026.

How has the price of METHOTREXATE 50 MG/2 ML VIAL changed over time?

Over the history we have for it, the NADAC for METHOTREXATE 50 MG/2 ML VIAL has risen 32.0%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for METHOTREXATE 50 MG/2 ML VIAL?

Since Nov 28, 2013, the NADAC for METHOTREXATE 50 MG/2 ML VIAL has ranged from a low of $2.4714 (Nov 28, 2013) to a high of $3.5278 (Jul 15, 2015), with a median of $3.1986 per ML.

Are there cheaper alternatives to METHOTREXATE 50 MG/2 ML VIAL?

Yes. 4 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, METHOTREXATE 1 GRAM/40 ML VIAL, is $0.6450 per ML — about 80% below METHOTREXATE 50 MG/2 ML VIAL.

Who manufactures METHOTREXATE 50 MG/2 ML VIAL?

METHOTREXATE 50 MG/2 ML VIAL (NDC 61703035038) is labeled by Hospira Inc., and CMS classifies it as a generic product.