Product Information

BUPROPION HCL XL 300 MG TABLET is a generic product labeled by Sun Pharmaceutical Industries Inc., priced at $0.1033 per EA under NDC 63304072430. Its NADAC has been published 259 times since Mar 10, 2021.

FDA first approved this application on Dec 31, 2020.

BUPROPION HCL XL 300 MG TABLET

Bupropion hydrochloride
$0.1033per EA

Strength

300 mg/1

NDC

63304072430

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

2/18/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA203650

FDA Approved

12/31/2020

On Market Since

1/1/2021

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 259 times since Mar 10, 2021, and over the history we have for it it has declined 51.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1033 per EA
All-time high$0.2232 (Jun 16, 2021)
All-time low$0.1033 (Feb 18, 2026)
52-week high$0.1492
52-week low$0.1033
Median price$0.1624
Average price$0.1661
Largest weekly change-27.4% (Feb 21, 2024)
Weeks tracked259
Tracking sinceMar 10, 2021

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

-30.3%

3Y

-42.0%

5Y

-50.0%

All

-51.6%

Last surveyed Feb 18, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 2% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by Sun Pharmaceutical Industries Inc., is $0.1033 per EA (NDC 63304072430), effective Feb 18, 2026.

How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 51.6%. It has been tracked across 259 weekly CMS publications since Mar 10, 2021.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?

Since Mar 10, 2021, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1033 (Feb 18, 2026) to a high of $0.2232 (Jun 16, 2021), with a median of $0.1624 per EA.

Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?

Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BUPROPION HCL XL 300 MG TABLET, is $0.1014 per EA — about 2% below BUPROPION HCL XL 300 MG TABLET.

Who manufactures BUPROPION HCL XL 300 MG TABLET?

BUPROPION HCL XL 300 MG TABLET (NDC 63304072430) is labeled by Sun Pharmaceutical Industries Inc., and CMS classifies it as a generic product.