Product Information

BUPROPION HCL XL 300 MG TABLET is a generic product labeled by BluePoint Laboratories, priced at $0.1014 per EA under NDC 68001061403. Its NADAC has been published 122 times since Apr 24, 2024.

FDA first approved this application on Feb 2, 2022. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

BUPROPION HCL XL 300 MG TABLET

Bupropion hydrochloride
$0.1014per EA

Strength

300 mg/1

NDC

68001061403

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA215568

FDA Approved

2/2/2022

TE Code

AB3

On Market Since

4/9/2024

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 122 times since Apr 24, 2024, and over the history we have for it it has declined 33.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1014 per EA
All-time high$0.1676 (Jul 10, 2024)
All-time low$0.1014 (Aug 19, 2026)
52-week high$0.1492
52-week low$0.1014
Median price$0.1385
Average price$0.1362
Largest weekly change-23.7% (Nov 20, 2024)
Weeks tracked122
Tracking sinceApr 24, 2024

Price History

1W

-2.6%

1M

-9.1%

3M

-12.2%

6M

-1.9%

1Y

-32.0%

3Y

N/A

5Y

N/A

All

-33.1%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by BluePoint Laboratories, is $0.1014 per EA (NDC 68001061403), effective Aug 19, 2026.

How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 33.1%. It has been tracked across 122 weekly CMS publications since Apr 24, 2024.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?

Since Apr 24, 2024, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1014 (Aug 19, 2026) to a high of $0.1676 (Jul 10, 2024), with a median of $0.1385 per EA.

Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL XL 300 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures BUPROPION HCL XL 300 MG TABLET?

BUPROPION HCL XL 300 MG TABLET (NDC 68001061403) is labeled by BluePoint Laboratories, and CMS classifies it as a generic product.