Product Information
TRETINOIN 0.1% CREAM is a generic product labeled by Viona Pharmaceuticals Inc., priced at $0.7625 per GM under NDC 72578015308. Its NADAC has been published 79 times since Feb 19, 2025.
FDA first approved this application on Apr 25, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1 mg/g
Manufacturer
Viona Pharmaceuticals Inc.NDC
72578015308
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
TRETINOINApproval Type
Generic (ANDA)
FDA Application
ANDA218561FDA Approved
4/25/2024
TE Code
AB
On Market Since
4/30/2024
Pharmacological Classes
Price Statistics
The NADAC for TRETINOIN 0.1% CREAM has been published 79 times since Feb 19, 2025, and over the history we have for it it has declined 37.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.7625 per GM |
|---|---|
| All-time high | $1.2838 (Apr 16, 2025) |
| All-time low | $0.7625 (Aug 19, 2026) |
| 52-week high | $1.1996 |
| 52-week low | $0.7625 |
| Median price | $0.9589 |
| Average price | $1.0516 |
| Largest weekly change | -8.7% (Oct 22, 2025) |
| Weeks tracked | 79 |
| Tracking since | Feb 19, 2025 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TRETINOIN 0.1% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for TRETINOIN 0.1% CREAM, manufactured by Viona Pharmaceuticals Inc., is $0.7625 per GM (NDC 72578015308), effective Aug 19, 2026.
How has the price of TRETINOIN 0.1% CREAM changed over time?
Over the history we have for it, the NADAC for TRETINOIN 0.1% CREAM has declined 37.5%. It has been tracked across 79 weekly CMS publications since Feb 19, 2025.
What are the highest and lowest recorded NADAC prices for TRETINOIN 0.1% CREAM?
Since Feb 19, 2025, the NADAC for TRETINOIN 0.1% CREAM has ranged from a low of $0.7625 (Aug 19, 2026) to a high of $1.2838 (Apr 16, 2025), with a median of $0.9589 per GM.
Are there cheaper alternatives to TRETINOIN 0.1% CREAM?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TRETINOIN 0.1% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures TRETINOIN 0.1% CREAM?
TRETINOIN 0.1% CREAM (NDC 72578015308) is labeled by Viona Pharmaceuticals Inc., and CMS classifies it as a generic product.